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Cervical cancer nearly always involves human papillomavirus (HPV) infection. [45] [46] HPV is a virus with numerous strains, several of which predispose to precancerous changes in the cervical epithelium, particularly in the transformation zone, which is the most common area for cervical cancer to start. [47]
In most women, the long axis of the uterus is bent forward on the long axis of the vagina, against the urinary bladder. This position is referred to as anteversion of the uterus. Furthermore, the long axis of the body of the uterus is bent forward at the level of the internal os with the long axis of the cervix.
In females, the uterus, fallopian tubes, ovaries and upper vagina occupy the area between the other viscera. [1] [2] The rectum is located at the back of the pelvis, in the curve of the sacrum and coccyx; the bladder is in front, behind the pubic symphysis. The pelvic cavity also contains major arteries, veins, muscles, and nerves.
The vesicouterine pouch is a fold of peritoneum over the uterus and the bladder, forming a pelvic recess. [1] It is continued over the intestinal surface and body of the uterus onto its vesical surface, which it covers as far as the junction of the body and cervix uteri, and then to the bladder.
The uterine arteries reach the margins of the cervix in this fibrous tissue, while on either side the ureter runs downward and forward in it at a distance of about 2 cm. from the cervix. Posteriorly, the supravaginal cervix is covered by peritoneum, which is prolonged below on to the posterior vaginal wall, when it is reflected on to the rectum ...
It is important in providing support for pelvic viscera (organs), e.g. the bladder, intestines, the uterus (in females), and in maintenance of continence as part of the urinary and anal sphincters. It facilitates birth by resisting the descent of the presenting part, causing the fetus to rotate forwards to navigate through the pelvic girdle.
Retroverted uterus; Other names: Tipped uterus: A transvaginal ultrasound showing a retroverted uterus during pregnancy. The cervix lies posteriorly to the urinary bladder, and the uterus normally extends superiorly from it, but the direction of the body of the fetus reveals that the uterus extends backwards.
The front is known as the "vesical layer". It forms the anterior and lateral ligaments of the bladder. In males, its middle lamina crosses the floor of the pelvis between the rectum and vesiculæ seminales as the rectovesical septum; in the female this is perforated by the cervix and is named the transverse cervical ligament.