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Isosorbide dinitrate is in the nitrate family of medications and works by dilating blood vessels. [1] Isosorbide dinitrate was first written about in 1939. [3] It is on the World Health Organization's List of Essential Medicines. [4] Isosorbide dinitrate is available as a generic medication. [1] [5] A long-acting form exists. [1]
Ingesting too much nitrite and/or nitrate through well water is suspected to cause methemoglobinemia. [17] 95% of the nitrite ingested in modern diets comes from bacterial conversion of nitrates naturally found in vegetables. [18] However, potentially cancer-causing nitroso compounds are not made in the pH-neutral colon.
Organic nitrites are prepared from alcohols and sodium nitrite in sulfuric acid solution.They decompose slowly on standing, the decomposition products being oxides of nitrogen, water, the alcohol, and polymerization products of the aldehyde. [1]
The first long-acting (depot) injections were antipsychotics fluphenazine and haloperidol. [2] The concept of a depot injection arose before 1950, and originally was used to describe antibiotic injections that lasted longer to allow for less frequent administration.
Erythritol tetranitrate (ETN) is an explosive compound chemically similar to PETN, [1] though it is thought to be slightly more sensitive to friction and impact.. Like many nitrate esters, ETN acts as a vasodilator, and was the active ingredient in the original "sustained release" tablets, made under a process patent in the early 1950s, called "nitroglyn".
Hydroxylammonium nitrate or hydroxylamine nitrate (HAN) is an inorganic compound with the chemical formula [NH 3 OH] + [NO 3] −. It is a salt derived from hydroxylamine and nitric acid. In its pure form, it is a colourless hygroscopic solid. It has potential to be used as a rocket propellant either as a solution in monopropellants or ...
Praseodymium(III) nitrate is any inorganic compound with the chemical formula Pr(NO 3) 3 ·xH 2 O. These salts are used in the extraction and purification of praseodymium from its ores. [2] The hexahydrate has been characterized by X-ray crystallography. [3] Praseodymium nitrate can be prepared by treating praseodymium oxide with nitric acid:
Samarium(III) nitrate is an odorless, white-colored chemical compound with the formula Sm(NO 3) 3. It forms the hexahydrate, which decomposes at 50°C to the anhydrous form. When further heated to 420°C, it is converted to the oxynitrate, and at 680°C it decomposes to form samarium(III) oxide. [2]