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Drug-induced angioedema is a known complication of the use of angiotensin-converting enzyme (ACE) inhibitors, angiotensin II antagonists (ARBs), and Angiotensin-Neprilysin Inhibitor LCZ969. [ 1 ] : 120 The angioedema appears to be dose dependent as it may resolve with decreased dose.
In people with ACE inhibitor angioedema, the drug needs to be discontinued and an alternative treatment needs to be found, such as an angiotensin II receptor blocker (ARB), [17] which has a similar mechanism but does not affect bradykinin. However, this is controversial, as small studies have shown some patients with ACE inhibitor angioedema ...
Treatment of acquired angioedema is separated into two main parts. First controlling acute symptoms during angioedema attacks is crucial for preventing and lowering the risk of mortality. [ 20 ] Second, managing AAE chronically with prophylactic treatment is important to improve prognosis and quality of life. [ 20 ]
Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a class of medication used primarily for the treatment of high blood pressure and heart failure. [1] [2] This class of medicine works by causing relaxation of blood vessels as well as a decrease in blood volume, which leads to lower blood pressure and decreased oxygen demand from the heart.
Lisinopril is a medication belonging to the drug class of angiotensin-converting enzyme (ACE) inhibitors and is used to treat hypertension (high blood pressure), heart failure, and heart attacks. [7] For high blood pressure it is usually a first-line treatment. It is also used to prevent kidney problems in people with diabetes mellitus. [7]
[1] [3] It is a first line treatment for high blood pressure. [3] It is taken by mouth. [1] [3] Common side effects include headaches, dizziness, feeling tired, and cough. [3] Serious side effects may include liver problems, low blood pressure, angioedema, kidney problems, and high blood potassium. [3] Use in pregnancy and breastfeeding is not ...