Ad
related to: lamin b1 irradiated tissue staining techniquesscbt.com has been visited by 10K+ users in the past month
Search results
Results From The WOW.Com Content Network
4001 16906 Ensembl ENSG00000113368 ENSMUSG00000024590 UniProt P20700 P14733 RefSeq (mRNA) NM_001198557 NM_005573 NM_010721 RefSeq (protein) NP_001185486 NP_005564 NP_034851 Location (UCSC) Chr 5: 126.78 – 126.84 Mb Chr 18: 56.84 – 56.89 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene. The nuclear lamina consists of ...
The very first modification involving farnesylation of prelamin A is crucial to the development of mature lamin A. Isoform lamin C does not undergo posttranslational modifications. [ 9 ] [ 13 ] Some studies have demonstrated that lamins A and C are not required for the formation of the nuclear lamina, yet disruptions in the LMNA gene can ...
The presence of lamin polypeptides is a property of all animals. The nuclear lamin-associated membrane proteins are either integral or peripheral membrane proteins. The most important are lamina associated polypeptides 1 and 2 (LAP1, LAP2), emerin, lamin B-receptor (LBR), otefin and MAN1. Due to their positioning within or their association ...
Through these interactions, laminins critically contribute to cell attachment and differentiation, cell shape and movement, maintenance of tissue phenotype, and promotion of tissue survival. [ 4 ] [ 6 ] Some of these biological functions of laminin have been associated with specific amino-acid sequences or fragments of laminin. [ 4 ]
3912 16777 Ensembl ENSG00000091136 ENSMUSG00000002900 UniProt P07942 P02469 RefSeq (mRNA) NM_002291 NM_008482 RefSeq (protein) NP_002282 NP_032508 Location (UCSC) Chr 7: 107.92 – 108 Mb Chr 12: 31.32 – 31.38 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Laminin subunit beta-1 is a protein that in humans is encoded by the LAMB1 gene. Laminins, a family of extracellular matrix ...
Immunohistochemistry or IHC staining of tissue sections (or immunocytochemistry, which is the staining of cells), is perhaps the most commonly applied immunostaining technique. [2] While the first cases of IHC staining used fluorescent dyes (see immunofluorescence ), other non-fluorescent methods using enzymes such as peroxidase (see ...
Mutations in the lamin rod domain leading to mislocalization of both lamin A and emerin occur in patients with autosomal dominant forms of muscular dystrophy and cardiomyopathy. [ citation needed ] Most lamin B mutations appear to be lethal with mutations in lamin B1 causing death at birth in mice. [ 3 ]
Immunofluorescence (IF) is a light microscopy-based technique that allows detection and localization of a wide variety of target biomolecules within a cell or tissue at a quantitative level. The technique utilizes the binding specificity of antibodies and antigens. [1] The specific region an antibody recognizes on an antigen is called an ...
Ad
related to: lamin b1 irradiated tissue staining techniquesscbt.com has been visited by 10K+ users in the past month