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The growing knowledge behind the mechanism of autocrine signaling in cancer progression has revealed new approaches for therapeutic treatment. For example, autocrine Wnt signaling could provide a novel target for therapeutic intervention by means of Wnt antagonists or other molecules that interfere with ligand-receptor interactions of the Wnt ...
Autocrine signaling is a special case of paracrine signaling where the secreting cell has the ability to respond to the secreted signaling molecule. [9] Synaptic signaling is a special case of paracrine signaling (for chemical synapses ) or juxtacrine signaling (for electrical synapses ) between neurons and target cells.
In cell biology, there are a multitude of signalling pathways. Cell signalling is part of the molecular biology system that controls and coordinates the actions of cells. Akt/PKB signalling pathway; AMPK signalling pathway; cAMP-dependent pathway; Eph/ephrin signalling pathway; Hedgehog signalling pathway; Hippo signalling pathway
A phenomenon called "AHL priming", which is a dependent signalling pathway, enhanced our knowledge of long-chain AHLs. The role of quorum-sensing molecules was better explained according to three categories: host physiology–based impact of quorum sensing molecules; ecological effects; and cellular signaling.
Secondary messenger systems can be synthesized and activated by enzymes, for example, the cyclases that synthesize cyclic nucleotides, or by opening of ion channels to allow influx of metal ions, for example Ca 2+ signaling. These small molecules bind and activate protein kinases, ion channels, and other proteins, thus continuing the signaling ...
In cellular biology, paracrine signaling is a form of cell signaling, ... The Wnt signaling pathways are complex, involving many different elements, and therefore ...
In cell biology, a biological pathway is a series of interactions among molecules in a cell that leads to a certain product or a change in the cell. Such a pathway can trigger the assembly of new molecules, such as a fat or protein. Pathways can also turn genes on and off, or spur a cell to move. [1]
For example, 'pathway' can denote a metabolic pathway involving a sequence of enzyme-catalyzed reactions of small molecules, or a signaling pathway involving a set of protein phosphorylation reactions and gene regulation events. Therefore, the term "pathway analysis" has a very broad application.