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Here, a top doctor discusses treatments and side effects. ... Dr. Mandel: There are about 170 clinical studies on ketamine therapy for depression and other mental health conditions. The results ...
Current ketamine treatment is in the form of a nasal spray (in the form of esketamine) or injection. ... However, eight participants reported severe side effects, including severe depression ...
Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, [10] [12] is the S(+) enantiomer of ketamine. [5] [13] It is a dissociative hallucinogen drug used as a general anesthetic and as an antidepressant for treatment of depression.
The Food and Drug Administration (FDA) recently approved the nasal spray Spravato for the treatment of major depression in people who have not responded to at least two oral antidepressants.
Due to the risks of certain side effects of the drug, including abuse and misuse, a person must administer the nasal spray in a clinic or doctor’s office under medical supervision. Alternative ...
Ketamine potentiates the sedative effects of propofol [86] and midazolam. [87] Naltrexone potentiates psychotomimetic effects of a low dose of ketamine, [88] while lamotrigine [38] and nimodipine [39] decrease them. Clonidine reduces the increase of salivation, heart rate, and blood pressure during ketamine anesthesia and decreases the ...
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