Search results
Results From The WOW.Com Content Network
Congenital stationary night blindness (CSNB) can be inherited in an X-linked, autosomal dominant, or autosomal recessive pattern, depending on the genes involved. Two forms of CSNB can also affect horses, one linked to the leopard complex of equine coat colors and the other found in certain horse breeds. Both are autosomal recessives.
Congenital stationary night blindness has been linked with the leopard complex since the 1970s. [14] The presence of CSNB in non-leopard breeds and horses suggested that the two conditions might be located on close, but separate genes.
Congenital stationary night blindness (CSNB) is usually diagnosed based on the owner's observations, but some horses have visibly abnormal eyes: poorly aligned eyes (dorsomedial strabismus) or involuntary eye movement (nystagmus). [8] In horses, CSNB has been linked with the leopard complex color pattern since the 1970s. [9]
Homozygous leopards are substantially more prone to congenital stationary night blindness. [9] Congenital stationary night blindness is present at birth and is characterized by impaired vision in dark conditions.
"Moon blindness" on an Icelandic horse Advanced stage of disease Advanced stage of disease ERU on an Icelandic horse. Equine recurrent uveitis (ERU) – also known as moon blindness, recurrent iridocyclitis, or periodic ophthalmia [1] – is an acute, nongranulomatous inflammation of the uveal tract of the eye, occurring commonly in horses of all breeds, worldwide.
The complete form of congenital stationary night blindness is due to the absence of nyctalopin. [16] This absence is due to a mutation involving an 85 base pair deletion. [ 17 ] In humans, more than 30 mutations are found in the NYX gene and most of them have an impact either on the tertiary structure of the LRR domains of nyctalopin or to ...
Twilight, the Thoroughbred mare who was the first horse to have its genome fully sequenced. The horse genome was first sequenced in 2006. The Horse Genome Project mapped 2.7 billion DNA base pairs, [1] and released the full map in 2009. [2] The horse genome is larger than the dog genome, but smaller than the human genome or the bovine genome. [2]
For this reason, blindness in animals is a unique topic of study. In general, nocturnal or subterranean animals have less interest in the visual world, and depend on other sensory modalities . Visual capacity is a continuum, with humans falling somewhere in the center.