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When conducting a dihybrid test cross, two dominant phenotypic characteristics are selected and crossed with parents displaying double recessive traits. The phenotypic characteristics of the F1 generation are then analyzed. In such a test cross, if the individual being tested is heterozygous, a phenotypic ratio of 1:1:1:1 is typically observed. [7]
A simple example to illustrate genotype as distinct from phenotype is the flower colour in pea plants (see Gregor Mendel). There are three available genotypes, PP (homozygous dominant), Pp (heterozygous), and pp (homozygous recessive). All three have different genotypes but the first two have the same phenotype (purple) as distinct from the ...
In medical genetics, compound heterozygosity is the condition of having two or more heterogeneous recessive alleles at a particular locus that can cause genetic disease in a heterozygous state; that is, an organism is a compound heterozygote when it has two recessive alleles for the same gene, but with those two alleles being different from each other (for example, both alleles might be ...
The words homozygous, heterozygous, and hemizygous are used to describe the genotype of a diploid organism at a single locus on the DNA. Homozygous describes a genotype consisting of two identical alleles at a given locus, heterozygous describes a genotype consisting of two different alleles at a locus, hemizygous describes a genotype consisting of only a single copy of a particular gene in an ...
A transheterozygote is a diploid organism that is heterozygous at two different loci (genes). Each of the two loci has one natural (or wild type) allele and one allele that differs from the natural allele because of a mutation. Such an organism can be created by crossing together two organisms that carry one mutation each, in two different ...
For example, using 'A' as the representative character for each allele, a homozygous dominant pair's genotype would be depicted as 'AA', while homozygous recessive is shown as 'aa'. Heterozygosity, with hetero associated with different , can only be 'Aa' (the capital letter is always presented first by convention).
An example in dog coat genetics is the homozygosity with the allele "e e" on the Extension-locus making it impossible to produce any other pigment than pheomelanin. Although the allele "e" is a recessive allele on the extension-locus itself, the presence of two copies leverages the dominance of other coat colour genes.
In the example pictured to the right, RRYY/rryy parents result in F 1 offspring that are heterozygous for both R and Y (RrYy). [4] This is a dihybrid cross of two heterozygous parents. The traits observed in this cross are the same traits that Mendel was observing for his experiments. This cross results in the expected phenotypic ratio of 9:3:3:1.