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Tocolytics are used in preterm labor, which refers to when a baby is born too early before 37 weeks of pregnancy. As preterm birth represents one of the leading causes of neonatal morbidity and mortality, the goal is to prevent neonatal morbidity and mortality through delaying delivery and increasing gestational age by gaining more time for other management strategies like corticosteroids ...
As the fetal hypothalamus matures, the activation of the hypothalamic–pituitary–adrenal (HPA) axis initiates labor through two hormonal mechanisms. The end pathway of both mechanisms lead to contractions in the myometrium, a mechanical cause of placental separation, which is due to the sheer force and contractile and involutive changes that occur within the uterus, distorting the placentome.
Atosiban is used to delay birth in adult women who are 24 to 33 weeks pregnant, when they show signs that they may give birth pre-term (prematurely). [4] These signs include regular contractions lasting at least 30 seconds at a rate of at least four every 30 minutes, [4] and dilation of the cervix (the neck of the womb) of 1 to 3 cm and an effacement (a measure of the thinness of the cervix ...
In obstetrics, a cephalic presentation or head presentation or head-first presentation is a situation at childbirth where the fetus is in a longitudinal lie and the head enters the pelvis first; the most common form of cephalic presentation is the vertex presentation, where the occiput is the leading part (the part that first enters the birth canal). [1]
Labour induction is the process or treatment that stimulates childbirth and delivery. Inducing labour can be accomplished with pharmaceutical or non-pharmaceutical methods. Inductions are most often performed either with prostaglandin drug treatment alone, or with a combination of prostaglandin and intravenous oxytocin treatment. [95]
These labour contractions are characterized by their rhythmic tightening and relaxation of the myometrium, the most prominent uterine muscle. Labour contractions primarily serve the purpose of opening and dilating the cervix , [ 7 ] which leads to the assisting of the passage of the baby through the vaginal canal during the first stage of labour.
Progress of labor – A spontaneous, normally progressing, straightforward labor requiring no intervention is a favorable sign. [ 28 ] Second twins – If a first twin is born head down and the second twin is breech, the chances are good that the second twin can have a safe breech birth.
Presentation of twins in Der Rosengarten ("The Rose Garden"), a German standard medical text for midwives published in 1513. In obstetrics, the presentation of a fetus about to be born specifies which anatomical part of the fetus is leading, that is, is closest to the pelvic inlet of the birth canal.