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The general structure of a cardiac glycoside consists of a steroid molecule attached to a sugar and an R group. [4] The steroid nucleus consists of four fused rings to which other functional groups such as methyl, hydroxyl, and aldehyde groups can be attached to influence the overall molecule's biological activity. [4]
The following are medications commonly prescribed cardiac pharmaceutical agents. The specificity of the following medications is highly variable, and often are not particularly specific to a given class. As such, they are listed as are commonly accepted.
They can be categorised into four distinct groups based on their unique mechanisms of action: cardiac glycosides, beta-adrenergic agonists, phosphodiesterase III inhibitors, and calcium sensitizers. It is important to note that certain medications, such as Milrinone and Digoxin , possess overlapping classifications due to their ability to ...
These are a type of cardiac glycoside, the other being the cardenolide glycosides. Both bufadienolides and their glycosides are toxic; specifically, they can cause an atrioventricular block, bradycardia (slow heartbeat), ventricular tachycardia (a type of rapid heartbeat), and possibly lethal cardiac arrest. [1]
Pages in category "Cardiac glycosides" The following 8 pages are in this category, out of 8 total. This list may not reflect recent changes. ...
Digoxin is in the cardiac glycoside family of medications. [4] It was first isolated in 1930 from the foxglove plant, Digitalis lanata. [7] [8] It is on the World Health Organization's List of Essential Medicines. [9] In 2021, it was the 241st most commonly prescribed medication in the United States, with more than 1 million prescriptions. [10 ...
The term derives from card-"heart" (from Greek καρδία kardiā) and the suffix -enolide, referring to the lactone ring at C17. [2] Cardenolides are a class of steroids (or aglycones if viewed as cardiac glycoside constituents), and cardenolides are a subtype of this class (see MeSH D codes list).
ATC code C01 Cardiac therapy is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.