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  2. Digitoxin - Wikipedia

    en.wikipedia.org/wiki/Digitoxin

    Digitoxin is a cardiac glycoside used for the treatment of heart failure and certain kinds of heart arrhythmia. It is a phytosteroid and is similar in structure and effects to digoxin, though the effects are longer-lasting. Unlike digoxin, which is eliminated from the body via the kidneys, it is eliminated via the liver, and so can be used in ...

  3. Cardiac glycoside - Wikipedia

    en.wikipedia.org/wiki/Cardiac_glycoside

    Cardiac glycosides, such as the commonly used digoxin and digitoxin, deal with the latter, due to their positive inotropic activity. On the other hand, cardiac arrhythmia are changes in heart rate, whether faster ( tachycardia ) or slower ( bradycardia ).

  4. Digoxin - Wikipedia

    en.wikipedia.org/wiki/Digoxin

    Digoxin increased the risk of death in women by 23%. There was no difference in the death rate for men in the study. [38] Digoxin is also used as a standard control substance to test for P-glycoprotein inhibition. [39] Digoxin appears to be a peripherally selective drug due to limited brain uptake caused by binding to P-glycoprotein. [40] [41]

  5. Digitalis purpurea - Wikipedia

    en.wikipedia.org/wiki/Digitalis_purpurea

    However, digitoxin, digoxin and several other cardiac glycosides, such as ouabain, have narrow therapeutic windows (i.e., because of their steep dose-response curves, minute increases in the dosage of these drugs can make the difference between an ineffective dose and a fatal one).

  6. Digoxin toxicity - Wikipedia

    en.wikipedia.org/wiki/Digoxin_toxicity

    Digoxin immune Fab used to treat digoxin toxicity The primary treatment of digoxin toxicity is digoxin immune fab , which is an antibody made up of anti-digoxin immunoglobulin fragments. This antidote has been shown to be highly effective in treating life-threatening signs of digoxin toxicity such as hyperkalemia, hemodynamic instability, and ...

  7. Cardenolide - Wikipedia

    en.wikipedia.org/wiki/Cardenolide

    digitoxin; digitoxigenin; digoxigenin; digoxin; medigoxin; neoconvalloside; ouabain; strophanthidin; Bufadienolide and marinobufagenin are similar in structure and function. Cardanolide is the same core structure, but has a saturated lactone ring instead of one containing an alkene.

  8. Phytosteroid - Wikipedia

    en.wikipedia.org/wiki/Phytosteroid

    Digitoxin, a phytosteroid and cardiac glycoside found in digitalis. Phytosteroids, also known as plant steroids, are naturally occurring steroids that are found in plants. [1] Examples include digoxin, digitoxin, diosgenin, and guggulsterone, as well as phytosterols like β-sitosterol and other phytoestrogens like isoflavones. [1]

  9. List of side effects of digoxin - Wikipedia

    en.wikipedia.org/.../List_of_side_effects_of_digoxin

    An unusual side effect of digoxin is a disturbance of color vision (mostly yellow and green) called xanthopsia. Vincent van Gogh's "Yellow Period" may have somehow been influenced by concurrent digitalis therapy. Other oculotoxic effects of digoxin include generalized blurry vision, as well as seeing a "halo" around each point of light.