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The oxygen affinity of the blood is related to lung volume. Where the lungs do not represent an oxygen store, the oxygen affinity is low to maximise the unloading of oxygen and to maintain a high tissue oxygen tension. Where the lungs are utilised as an oxygen store, the affinity is high and maximises uptake of oxygen from the alveolar volume. [13]
The fish draws oxygen-rich water in through the mouth (left). It then pumps it over gills so oxygen enters the bloodstream, and allows oxygen-depleted water to exit through the gill slits (right) In bony fish, the gills lie in a branchial chamber covered by a bony operculum. The great majority of bony fish species have five pairs of gills ...
Higher than normal concentrations of oxygen lead to increased levels of reactive oxygen species. [60] Oxygen is necessary for cell metabolism, and the blood supplies it to all parts of the body. When oxygen is breathed at high partial pressures, a hyperoxic condition will rapidly spread, with the most vascularised tissues being most vulnerable.
The result of breathing increased partial pressures of oxygen is hyperoxia, an excess of oxygen in body tissues. The body is affected in different ways depending on the type of exposure. Central nervous system toxicity is caused by short exposure to high partial pressures of oxygen at greater than atmospheric pressure.
Although total liquid ventilation (TLV) with completely liquid-filled lungs can be beneficial, [9] the complex liquid-filled tube system required is a disadvantage compared to gas ventilation—the system must incorporate a membrane oxygenator, heater, and pumps to deliver to, and remove from the lungs tidal volume aliquots of conditioned perfluorocarbon (PFC).
After being carried in blood to a body tissue in need of oxygen, O 2 is handed off from the heme group to monooxygenase, an enzyme that also has an active site with an atom of iron. [9] Monooxygenase uses oxygen for many oxidation reactions in the body. Oxygen that is suspended in the blood plasma equalizes into the tissue according to Henry's law.
This is likely due to lactose intolerance, a condition making it hard to digest lactose, a sugar found in dairy products. Most newborns are able to produce lactase, an enzyme crucial for the ...
Atmospheric nitrogen has a partial pressure of approximately 0.78 bar at sea level. Air in the alveoli of the lungs is diluted by saturated water vapour (H 2 O) and carbon dioxide (CO 2), a metabolic product given off by the blood, and contains less oxygen (O 2) than atmospheric air as some of it is taken up by the blood for metabolic use. The ...