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Much research has been done into the use of a rat model to show how Borna virus infection, [17] [18] exposure to valproic acid in utero, [19] and maternal immune activation [20] may cause autism. Another goal of the use of rodent models to study autism is to identify the mechanism by which autism develops in humans. [ 1 ]
Autism, also called autism spectrum disorder (ASD) or autism spectrum condition (ASC), is a neurodevelopmental disorder characterized by symptoms of deficient reciprocal social communication and the presence of restricted, repetitive, and inflexible patterns of behavior. While its severity and specific manifestations vary widely across the ...
A 2013 meta-analysis indicated that TEACCH has small or no effects on perceptual, motor, verbal, cognitive, and motor functioning, communication skills, and activities of daily living. There were positive effects in social and maladaptive behavior, but these results required further replication due to the methodological limitations of the pool ...
The scientific study of the causes of developmental disorders involves many theories. Some of the major differences between these theories involves whether environment disrupts normal development, if abnormalities are pre-determined, or if they are products of human evolutionary history which become disorders in modern environments (see evolutionary psychiatry). [5]
An active area of neuroimaging research involves examining the functional connectivity of spatially remote brain regions. Functional connectivity analyses allow the characterization of interregional neural interactions during particular cognitive or motor tasks or merely from spontaneous activity during rest.
The IACC Strategic Plan was designed to detail research opportunities centered on the six most pressing questions facing those affected by autism and links them to specific research efforts. In 2009, the plan was finalized and submitted to the Secretary of the Department of Health and Human Services; a seventh question related to infrastructure ...
Research using an animal model of obsessive-compulsive disorder employed a standardized paradigm where the behavior of rats in a large open field was video recorded for 55 min on each test. Rat Macroscopic Video Obsessive-compulsive disorder No [2] Allen Brain Atlas: Atlas, stained sections from brains showing development and gene expression
The underconnectivity theory of autism posits that autistic people tend to have fewer high-level neural connections and less global synchronization, along with an excess of low-level processes. [31] Functional connectivity studies have found both hypo- and hyperconnectivity in brains of autistic people. [ 32 ]