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Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine, benztropine, diphenhydramine, and trihexyphenidyl.
EXD is commonly observed in psychostimulant abusers as these drugs directly impact the dopaminergic transporters, increasing the extracellular dopamine levels. [21] [6] Amplified excitation of the dopaminergic systems can induce extreme fear and magnify both approach and avoidance behaviors. [6]
The loss of dopamine with age is thought to be responsible for many neurological symptoms that increase in frequency with age, such as decreased arm swing and increased rigidity. [41] Changes in dopamine levels may also cause age-related changes in cognitive flexibility .
Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS) and are implicated in many neurological processes, including motivational and incentive salience, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling.
Tardive dyskinesia occurs as a result of long-term use of dopamine-receptor-blocking medications such as antipsychotics and metoclopramide. [1] [2] These medications are usually used for mental illness but may also be given for gastrointestinal or neurological problems. [1] The condition typically develops only after months to years of use.
Dopamine detox is "a pop culture idea, which [involves] abstaining from activities that stimulate a lot of pleasure, such as social media, gaming, porn, and certain foods," in an attempt to ...
Elderly people often experience multiple comorbidities that may contribute to the phenomenon of sundowning syndrome through neurodegeneration. Neurological disorders: Alzheimer's disease, Parkinson's disease , Huntington's disease , Lewy body dementia , fronto-temporal dementia, subcortical dementia.
High blood sugar levels. Medical professionals can diagnose high blood sugar with a blood test. Some of the symptoms can include fatigue, frequent urination, and increased thirst.