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Phentermine is an norepinephrine and dopamine releasing agent (NDRA) and produces stimulant, rewarding, and appetite suppressant effects. [8] [9] [10] Chemically, it is a substituted amphetamine. [11] Phentermine was approved for medical use in the United States in 1959. [3] It is available as a generic medication. [3]
Tesofensine primarily acts as an appetite suppressant, [8] but possibly also acts by increasing resting energy expenditure. [9] A recent study showed that tesofensine modulates neuronal activity of the lateral hypothalamus, silencing GABAergic neurons, [8] a brain region involve on feeding. Phase II clinical trials for the treatment of obesity ...
Phentermine is a stimulant and appetite suppressant. [3] Topiramate is an anticonvulsant that has weight loss side effects. [ 3 ] The exact mechanism of action for both drugs is unknown.
Ozempic is an FDA-approved medication for people who have type 2 diabetes. It’s often prescribed “off-label” for weight loss — when a drug is prescribed for something it’s not approved for.
This is a combination of an appetite suppressant called phentermine and an anticonvulsant called topiramate. Phentermine-topiramate is effective for weight loss and seems to reduce blood pressure ...
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