Ad
related to: host defense peptides wikipedia page free lookup tool number of words
Search results
Results From The WOW.Com Content Network
Animal models indicate that host defense peptides are crucial for both prevention and clearance of infection. It appears as though many peptides initially isolated as and termed "antimicrobial peptides" have been shown to have more significant alternative functions in vivo (e.g. hepcidin [18]). Dusquetide for example is an immunomodulator that ...
Defensin mimetics, also called host defense peptide (HDP) mimetics, are completely synthetic, non-peptide, small molecule structures that mimic defensins in structure and activity. [51] Similar molecules, such as brilacidin , are being developed as antibiotics , [ 52 ] anti-inflammatories for oral mucositis , [ 53 ] [ 54 ] and antifungals ...
Defensins are a family of microbicidal and cytotoxic peptides (antimicrobial peptides; AMP) that are involved in host defense, and help to maintain homeostasis of intestinal microbiota. DEFA5 is the main AMP that controls the enteric microbiota composition by selective killing of bacterial pathogens while preserving commensals.
A plant genome typically contains large numbers of different defensin genes [24] that vary in their efficacy against different pathogens and the amount they are expressed in different tissues. [25] In addition to their functions in the immune system, many of these low-molecular-weight peptides have developed additional roles in aiding ...
The Imd pathway is a broadly-conserved NF-κB immune signalling pathway of insects and some arthropods [1] that regulates a potent antibacterial defence response. The pathway is named after the discovery of a mutation causing severe immune deficiency (the gene was named "Imd" for "immune deficiency").
Dermcidin is a protein with 110 amino acids that in humans is encoded by the DCD gene. [3] [4] The full-length protein produces derived peptides as proteolysis-inducing factor (PIF) and other anti-microbial peptides, [4] secreted by human eccrine sweat glands onto the skin as a part of the innate host defense of the immune system.
Immunodominance is the immunological phenomenon in which immune responses are mounted against only a few of the antigenic peptides out of the many produced. [1] That is, despite multiple allelic variations of MHC molecules and multiple peptides presented on antigen presenting cells, the immune response is skewed to only specific combinations of the two. [1]
The phrase host defense peptides is somewhat controvesial, so I would recommend leaving the page as-is for the time being. There is currently a redirect from "Host defence peptide". I agree that they are more often called antimicrobial peptides. However, most immunologists are now calling them Host Defense Peptides because many have more than ...