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Likewise, combining injected tobramycin with other nephrotoxic or ototoxic drugs can lead to more adverse effects; examples include amphotericin B, ciclosporin, cisplatin, vancomycin, and the diuretic furosemide. Other diuretics can also increase the risk for side effects because they raise tobramycin concentrations in the body fluids. [8]
Common side effects when inhaled include wheezing, cough, and vomiting. [2] Serious side effects include Clostridioides difficile infection and allergic reactions including anaphylaxis. [2] Those who are allergic to other β-lactam have a low rate of allergy to aztreonam. [2] Use in pregnancy appears to be safe. [2]
Possible side effects [4] Mechanism of action Aminoglycosides; Amikacin: Amikin: Infections caused by Gram-negative bacteria, such as Escherichia coli and Klebsiella particularly Pseudomonas aeruginosa. Effective against aerobic bacteria (not obligate/facultative anaerobes) and tularemia. All aminoglycosides are ineffective when taken orally as ...
Side-effects of amikacin are similar to those of other aminoglycosides. Kidney damage and ototoxicity (which can lead to hearing loss) are the most important effects, occurring in 1–10% of users. [17] The nephro- and ototoxicity are thought to be due to aminoglycosides' tendency to accumulate in the kidneys and inner ear. [8] Diagram of the ...
Pulmonary drug delivery is mainly utilized for topical applications in the lungs, such as the use of inhaled beta-agonists, corticosteroids and anticholinergic agents for the treatment of asthma and COPD, the use of inhaled mucolytics and antibiotics for the treatment of cystic fibrosis (CT) and respiratory viral infections, [1] and the use of inhaled prostacyclin analogs for the treatment of ...
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Certain beverages can complement the effects of weight loss medications, support hydration and provide essential nutrients, while others may lead to unwanted side effects or make it harder to lose ...
Common side effects of the injectable form include kidney problems and neurological problems. [8] Other serious side effects may include anaphylaxis, muscle weakness, and Clostridioides difficile-associated diarrhea. [8] The inhaled form may result in constriction of the bronchioles. [8] It is unclear if use during pregnancy is safe for the ...