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  2. Familial atrial fibrillation - Wikipedia

    en.wikipedia.org/wiki/Familial_atrial_fibrillation

    Familial atrial fibrillation is an autosomal dominant heart condition that causes disruptions in the heart's normal rhythm. [ 1 ] [ 2 ] This condition is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria ), which causes the heartbeat to become fast and irregular.

  3. Atrial fibrillation - Wikipedia

    en.wikipedia.org/wiki/Atrial_fibrillation

    Atrial fibrillation is associated with an increased risk of heart failure, dementia, and stroke. [3] [12] It is a type of supraventricular tachycardia. [14] Atrial fibrillation frequently results from bursts of tachycardia that originate in muscle bundles extending from the atrium to the pulmonary veins. [15]

  4. Genome-wide association study - Wikipedia

    en.wikipedia.org/wiki/Genome-wide_association_study

    For example, a meta-analysis accomplished in 2018 revealed the discovery of 70 new loci associated with atrial fibrillation. It has been identified different variants associated with transcription factor coding-genes, such as TBX3 and TBX5 , NKX2-5 o PITX2 , which are involved in cardiac conduction regulation, in ionic channel modulation and ...

  5. Unmet Medical Need in Treatment of Heart Failure Patients ...

    www.aol.com/news/2013-02-06-unmet-medical-need...

    ARCA has identified common genetic variations that it believes predict individual patient response to Gencaro, giving it the potential to be the first genetically-targeted atrial fibrillation ...

  6. New Adaptive Phase 3 Trial Planned for GencaroTM in Atrial ...

    www.aol.com/news/2013-01-29-new-adaptive-phase-3...

    New Adaptive Phase 3 Trial Planned for Gencaro TM in Atrial Fibrillation BROOMFIELD, Colo.--(BUSINESS WIRE)-- ARCA biopharma, Inc. (NAS: ABIO) , a biopharmaceutical company developing genetically ...

  7. Gencaro TM Cardiovascular Effect on Patients with Atrial Fibrillation Paper Published in European Journal of Heart Failure BROOMFIELD, Colo.--(BUSINESS WIRE)-- ARCA biopharma, Inc. (NAS: ABIO ...