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Entamoeba histolytica is an anaerobic parasitic amoebozoan, part of the genus Entamoeba. [1] Predominantly infecting humans and other primates causing amoebiasis , E. histolytica is estimated to infect about 35-50 million people worldwide. [ 1 ]
The two most common manifestations of E histolytica include colitis (bloody stool with mucus, abdominal pain, and/or diarrhea), and discovery of a liver abscess on imaging. [2] Liver abscesses commonly present as right upper quadrant abdominal pain and fever, with worsening features associated with abscess rupture.
An ameboma, also known as an amebic granuloma, is a rare complication of Entamoeba histolytica infection, where in response to the infecting amoeba there is formation of annular colonic granulation, which results in a large local lesion of the bowel. [1]
E. histolytica cysts have a maximum of four nuclei, while the commensal Entamoeba coli cyst has up to 8 nuclei. Additionally, in E. histolytica, the endosome is centrally located in the nucleus, while it is usually off-center in Entamoeba coli. Finally, chromatoidal bodies in E. histolytica cysts are rounded, while they are jagged in Entamoeba ...
Chromatoidal bodies are aggregations of ribosomes found in cysts of some amoebae including Entamoeba histolytica and Entamoeba coli. They exist in the cytoplasm and are dark staining. In the early cystic stages of E. histolytica, chromatid bodies arise from aggregation of ribosomes forming polycrystalline masses. As the cyst matures, the masses ...
The genus Entamoeba was defined by Casagrandi and Barbagallo for the species Entamoeba coli, which is known to be a commensal organism. [2] Lösch's organism was renamed Entamoeba histolytica by Fritz Schaudinn in 1903; he later died, in 1906, from a self-inflicted infection when studying this amoeba.
They are indicative of a disease involving eosinophilic inflammation or proliferation, such as is found in allergic reactions (asthma, bronchitis, allergic rhinitis and rhinosinusitis) and parasitic infections such as Entamoeba histolytica, Necator americanus, and Ancylostoma duodenale.
It can be caused by Acanthamoeba [2] [3] or Entamoeba histolytica. [4]: 421 [5] When associated with Acanthamoeba, it is also known as "cutaneous acanthamoebiasis". [6] Balamuthia mandrillaris can also cause cutaneous amoebiasis, but can prove fatal if the amoeba enters the bloodstream [7] [8] It is characterized by ulcers. Diagnosis of ...