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  2. Amiodarone - Wikipedia

    en.wikipedia.org/wiki/Amiodarone

    Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of cardiac dysrhythmias. [4] This includes ventricular tachycardia, ventricular fibrillation, and wide complex tachycardia, atrial fibrillation, and paroxysmal supraventricular tachycardia. [4]

  3. Potassium channel blocker - Wikipedia

    en.wikipedia.org/wiki/Potassium_channel_blocker

    Amiodarone is also safe to use in individuals with cardiomyopathy and atrial fibrillation, to maintain normal sinus rhythm. Amiodarone prolongation of the action potential is uniform over a wide range of heart rates, so this drug does not have reverse use-dependent action. Amiodarone was the first agent described in this class. [4]

  4. Antiarrhythmic agent - Wikipedia

    en.wikipedia.org/wiki/Antiarrhythmic_agent

    Compounds that prolong the action potential: matching the modern classification, with the key drug example being amiodarone, and a surgical example being thyroidectomy. This was not a defining characteristic in an earlier review by Charlier et al. (1968), [ 17 ] but was supported by experimental data presented by Vaughan Williams (1970).

  5. Amiodarone induced thyrotoxicosis - Wikipedia

    en.wikipedia.org/wiki/Amiodarone_induced_thyro...

    Amiodarone induced thyrotoxicosis (AIT) is a form of hyperthyroidism due to treatment with antiarrhythmic drug, amiodarone. Amiodarone induced thyroid dysfunction more commonly results in hypothyroidism, estimated to occur in 6-32% of patients, whereas hyperthyroidism from amiodarone use is estimated at 1-12%. [1]

  6. Dronedarone - Wikipedia

    en.wikipedia.org/wiki/Dronedarone

    Dronedarone is less lipophilic than amiodarone, has a much smaller volume of distribution, and has an elimination half-life of 13–19 hours—this stands in contrast to amiodarone's half-life of several weeks. [2] [14] As a result of these pharmacokinetic characteristics, dronedarone dosing may be less complicated than amiodarone.

  7. List of side effects of digoxin - Wikipedia

    en.wikipedia.org/wiki/List_of_side_effects_of...

    Side effects can become more pronounced due to the drug interactions between digoxin and the following: Thiazide and loop diuretics, piperacillin, ticarcillin, amphotericin B, corticosteroids, and excessive laxative use. Amiodarone, some benzodiazepines, cyclosporine, diphenoxylate, indomethacin, itraconazole, propafenone, quinidine, quinine ...

  8. Pulmonary toxicity - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_toxicity

    As an example to illustrate what can be done, the use of the medicinal drug amiodarone: a) Prescribing the lowest possible dose of amiodarone leads to a lower incidence of pulmonary toxicity. [17] b) Regular monitoring, in order to diagnose any possible pulmonary toxicity early. [18] [19] c) Discontinuation as soon as pulmonary toxicity is ...

  9. Junctional ectopic tachycardia - Wikipedia

    en.wikipedia.org/wiki/Junctional_Ectopic_Tachycardia

    Amiodarone, propranolol, verapamil, flecainide, propafenone Junctional ectopic tachycardia ( JET ) is a rare syndrome of the heart that manifests in patients recovering from heart surgery . [ 1 ] It is characterized by cardiac arrhythmia , or irregular beating of the heart, caused by abnormal conduction from or through the atrioventricular node ...