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Demineralized bone matrix (DBM) is allograft bone that has had the inorganic mineral removed, leaving behind the organic "collagen" matrix. It was first discovered by Marshall Urist in 1965 that the removal of the bone mineral exposes more biologically active bone morphogenetic proteins . [ 1 ]
Bone grafting is a surgical procedure that replaces missing bone in order to repair bone fractures that are extremely complex, pose a significant health risk to the patient, or fail to heal properly. Some small or acute fractures can be cured without bone grafting, but the risk is greater for large fractures like compound fractures.
The surgery is quick (typically lasting between 30 and 90 minutes), minimally invasive, and can have a significantly shorter recovery time than an arthroplasty (knee replacement). Chronic articular cartilage defects do not heal spontaneously. [ 1 ]
Artificial bone refers to bone-like material created in a laboratory that can be used in bone grafts, to replace human bone that was lost due to severe fractures, disease, etc. [1] Bone fracture, which is a complete or partial break in the bone, is a very common condition that has more than three million US cases per year. [ 2 ]
Frederick Houdlette Albee (April 13, 1876 – February 15, 1945) was a surgeon who invented bone grafting and other advances in orthopedic surgery as a surgical treatment. He was also one of the fathers of rehabilitative medicine, a pioneer in physical, psychological and occupational rehabilitation.
Tommy John, for whom the surgery is named, in 2008. At the time of John's operation, Jobe estimated the chance for success of the operation at one in 100. [18] By 2009, the odds of complete recovery had risen to 85–92%. [19] Following his 1974 surgery, John missed the entire 1975 season rehabilitating his arm before returning for the 1976 season.
Five men have been sentenced to death by hanging in Nigeria's Kano state for the 2023 murder of a woman they accused of witchcraft. The convicted men attacked Dahare Abubakar, 67, as she was ...
Although there has been evidence that alloplasty is a viable method for repairing and substituting defects, there are disadvantages including suitability of patient bone quality and quantity for long term implant stability, possibility of rejection of the alloplastic implant, injuring surrounding nerves, cost of procedure and long recovery times.