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This microRNA database and microRNA targets databases is a compilation of databases and web portals and servers used for microRNAs and their targets. MicroRNAs (miRNAs) represent an important class of small non-coding RNAs (ncRNAs) that regulate gene expression by targeting messenger RNAs. [1]
StarBase also developed Pan-Cancer Analysis Platform to decipher Pan-Cancer Analysis Networks of lncRNAs, miRNAs, ceRNAs, and RNA-binding proteins (RBPs) by mining clinical and expression profiles of 14 cancer types (including more than six thousand samples) from The Cancer Genome Atlas (TCGA) Data Portal.
miRBase grew from the microRNA registry resource set up by Sam Griffiths-Jones in 2003. [7] According to Ana Kozomara and Sam Griffiths-Jones miRBase has five aims: [1] To provide a consistent naming system for microRNAs; To provide a central place collecting all known microRNA sequences; To provide human and computer readable information for ...
miRBase: the microRNA database; PolymiRTS: a database of DNA variations in putative microRNA target sites; PolyQ: database of polyglutamine repeats in disease and non-disease associated proteins; Rfam: a database of RNA families; IRESbase: A comprehensive database of experimentally validated internal ribosome entry sites. [14]
miRBase is considered to be the gold-standard miRNA database—it stores miRNA sequences detected by thousand of experiments. In this database each miRNA is associated with a miRNA precursor and with one or two mature miRNA (-5p and -3p). In the past it had always been said that the same miRNA precursor generates the same miRNA sequences.
In bioinformatics, TargetScan is a web server that predicts biological targets of microRNAs (miRNAs) by searching for the presence of sites that match the seed region of each miRNA. [1] For many species, other types of sites, known as 3'-compensatory sites [ 1 ] are also identified.
Cupid is a method for simultaneous prediction of miRNA-target interactions and their mediated competing endogenous RNA (ceRNA) interactions. It is an integrative approach significantly improves on miRNA-target prediction accuracy as assessed by both mRNA and protein level measurements in breast cancer cell lines.
Download QR code; Print/export ... CeRNA database; MicroRNA and microRNA target database ... MicroRNA biosensors; MicroRNA let-7a-2; Mir-1 microRNA precursor family ...
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