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Seltorexant (MIN-202, JNJ-42847922, JNJ-922) – selective OX 2 antagonist – under development for major depressive disorder, insomnia, and sleep apnea, up to phase 3 – half-life 2–3 hours [14] Tebideutorexant (JNJ-61393215, JNJ-3215) – selective OX 1 antagonist – under development for major depressive disorder, no development ...
Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [ 8 ] [ 9 ] It may also be used for hiccups and muscle spasms near the end of life, [ 9 ] and off-label to treat alcohol use disorder [ 10 ] [ 11 ] or opioid withdrawal symptoms. [ 12 ]
The man had sleep apnea—his airway was obstructed, which interrupted breathing at night, waking him repeatedly. But he refused Sullivan’s recommendation for surgery to create an opening in the ...
The respiratory disturbance index (RDI)—or respiratory distress Index—is a formula used in reporting polysomnography (sleep study) findings. Like the apnea-hypopnea index (AHI), it reports on respiratory distress events during sleep, but unlike the AHI, it also includes respiratory-effort related arousals (RERAs). [1]
The “sleepmaxxing” trend promotes hacks to enhance sleep, from avoiding blue light and maintaining a sleep routine to using mouth tape, nostril extenders, and supplements.
Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder and is characterized by recurrent episodes of complete or partial obstruction of the upper airway leading to reduced or absent breathing during sleep.