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Atorvastatin therapy can also help to prevent in-hospital dialysis post CM administration, however there is no evidence that it reduces all-cause mortality associated with CI-AKI. [32] [33] Overall, the evidence concludes that statin therapy, irrespective of the dose, is still more effective than no treatment or placebo at reducing the risk of ...
On average, statins can lower LDL cholesterol by 1.8 mmol/L (70 mg/dL), which translates into an estimated 60% decrease in the number of cardiac events (heart attack, sudden cardiac death) and a 17% reduced risk of stroke after long-term treatment. [36] A greater benefit is observed with high-intensity statin therapy. [37]
The NNT is the average number of patients who need to be treated to prevent one additional bad outcome. It is defined as the inverse of the absolute risk reduction , and computed as 1 / ( I u − I e ) {\displaystyle 1/(I_{u}-I_{e})} , where I u {\displaystyle I_{u}} is the incidence in the control (unexposed) group, and I e {\displaystyle I_{e ...
Type 2 statins Statins that are fully synthetic and have larger groups linked to the HMG-like moiety are often referred to as type 2 statins. One of the main differences between the type 1 and type 2 statins is the replacement of the butyryl group of type 1 statins by the fluorophenyl group of type 2 statins.
The effects of rosuvastatin on low-density lipoprotein (LDL) cholesterol are dose-related. Higher doses were more efficacious in improving the lipid profile of patients with hypercholesterolemia than milligram-equivalent doses of atorvastatin and milligram-equivalent or higher doses of simvastatin and pravastatin.
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A related term sealing current (aka wetting current or fritting current) is widely used in the telecommunication industry describing a small constant DC current (typically 1-20 mA) in copper wire loops in order to avoid contact oxidation of contacts and splices.
A new study found that Americans 40 and older could live over five years longer if they exercised as much as the top 25% of the population. Here's what to know.