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The sex of the fetus may be discerned by ultrasound as early as 11 weeks' gestation. The accuracy is relatively imprecise when attempted early. [15] [16] [17] After 13 weeks' gestation, a high accuracy of between 99% and 100% is possible if the fetus does not display intersex external characteristics. [18]
Ultrasound image of the foetus at 12 weeks of pregnancy in a sagittal scan. Measurements of fetal Crown Rump Length (CRL). The embryo and fetus float in the amniotic fluid inside the uterus of the mother usually in a curved posture resembling the letter C. The measurement can actually vary slightly if the fetus is temporarily stretching ...
Cell-free fetal DNA (cfDNA) Test/Noninvasive prenatal test (NIPT) (screen) [12] Week 10 – onward Less invasive Blood draw ~1–2 weeks Gender, chromosomal abnormalities Very low risk, however there is the potential for bruising, pain, nerve damage, fainting, haematoma, bacterial infection, and bloodborne pathogen exposure.
Screening for Down syndrome by a combination of maternal age and thickness of nuchal translucency in the fetus at 11–14 weeks of gestation was introduced in the 1990s. [7] This method identifies about 75% of affected fetuses while screening about 5% of pregnancies. Natural fetal loss after positive diagnosis at 12 weeks is about 30%. [6]
A meta-analysis published in 2011 found that such tests are reliable more than 98% of the time, as long as they are taken after the seventh week of pregnancy. [1] [2] Chorionic villus sampling (CVS) and amniocentesis are two rather invasive testing procedures. These may, in principle, be performed as early as the 8th and the 9th week of pregnancy.
The newer integrated screen (formerly called F.A.S.T.E.R for First And Second Trimester Early Results) can be done at 10 plus weeks to 13 plus weeks with an ultrasound of the fetal neck (thicker nuchal skin correlates with higher risk of Down syndrome being present) and two chemicals (analytes), pregnancy-associated plasma protein A and human ...
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[2] [48] Follow-up one week after the procedure is recommended to undergo ultrasound evaluation for fetal viability and assess healing of the puncture site. [48] Post-procedural pain and discomfort should be minimal and temporary and may be managed with acetaminophen. [2]