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Anticholinergic drugs are used to treat a variety of conditions: Dizziness (including vertigo and motion sickness-related symptoms) Extrapyramidal symptoms, a potential side-effect of antipsychotic medications; Gastrointestinal disorders (e.g., peptic ulcers, diarrhea, pyloro spasm, diverticulitis, ulcerative colitis, nausea, and vomiting)
Brompheniramine's effects on the cholinergic system may include side-effects such as drowsiness, sedation, dry mouth, dry throat, blurred vision, and increased heart rate. It is listed as one of the drugs of highest anticholinergic activity in a study of anticholinergenic burden, including long-term cognitive impairment.
The drug regulates behaviour and thoughts, and can also exhibit an anti-depressive effect. [3] [8] The side effect profile is similar to related antipsychotic agents, displaying weight gain, mental distress, and inability to sit still. Other possible symptoms include anticholinergic side effects such as insomnia, blurred vision, and dry mouth.
Drug-induced arrhythmia worsened by anticholinergics' side effect of tachycardia. Parkinson's disease, e.g. levodopa. Atropine decreases the absorption of levodopa. Preventing travel sickness, relieve stomach cramps or spasms, e.g. hyoscine. Additive effect. Nausea and vomiting, e.g. cyclizine. Additive effect.
Most common CNS disorders are highly polygenic in nature; that is, they are controlled by complex interactions between numerous gene products. As such, these conditions do not exhibit the single gene defect basis that is so attractive for the development of highly-specific drugs largely free of major undesirable side-effects ("the magic bullet ...
It has weak antipsychotic effects but is generally not used to treat psychoses. [3] It acts similar to chlorpromazine and causes sedation. [3] It has predominantly anticholinergic side effects, though extrapyramidal side effects are not uncommon. It belongs to the typical antipsychotic and phenothiazine class of drugs. [5]