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The irises of human eyes exhibit a wide spectrum of colours. Eye color is a polygenic phenotypic trait determined by two factors: the pigmentation of the eye's iris [1] [2] and the frequency-dependence of the scattering of light by the turbid medium in the stroma of the iris.
Despite the wide range of colors, the only pigment that contributes substantially to normal iris color is the dark pigment melanin. The quantity of melanin pigment in the iris is one factor in determining the phenotypic eye color of an organism. Structurally, this huge molecule is only slightly different from its equivalent found in skin and ...
The color of the mammalian, including human, iris is very variable. However, there are only two pigments present, eumelanin and pheomelanin . The overall concentration of these pigments, the ratio between them, variation in the distribution of pigment in the layers of the stroma of the iris and the effects of light scattering all play a part in ...
The inner layer of the optic cup is made of neuroepithelium (neural retina), while the outer layer is composed of retinal pigment epithelium (RPE). Experiments have determined that RPE cell differentiation and maintenance requires interaction with neighboring tissues, most likely canonical Wnt signaling, while neural retina differentiation is ...
Iris texture is a phenotypical feature that develops during gestation and remains unchanged after infancy. There is no evidence for changes in the iris pattern other than variations in pigmentation in the first years of life and variations caused by glaucoma treatment.
Some circle the circumference of the iris and the majority radiate toward the pupil. Blood vessels and nerves intersperse this mesh. In dark eyes, the stroma often contains pigment granules. Blue eyes and the eyes of albinos, however, lack pigment. Structure of the iris and surrounding parts showing the stroma of iris (stroma iridis).
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The macula (/ˈmakjʊlə/) [1] or macula lutea is an oval-shaped pigmented area in the center of the retina of the human eye and in other animals. The macula in humans has a diameter of around 5.5 mm (0.22 in) and is subdivided into the umbo, foveola, foveal avascular zone, fovea, parafovea, and perifovea areas.