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Cavernous hemangioma, also called cavernous angioma, venous malformation, or cavernoma, [1] [2] is a type of venous malformation due to endothelial dysmorphogenesis from a lesion which is present at birth. A cavernoma in the brain is called a cerebral cavernous malformation or CCM.
Cerebral cavernous malformation (CCM) is a cavernous hemangioma that arises in the central nervous system.It can be considered to be a variant of hemangioma, and is characterized by grossly large dilated blood vessels and large vascular channels, less well circumscribed, and more involved with deep structures, with a single layer of endothelium and an absence of neuronal tissue within the lesions.
A vascular malformation is a type of vascular anomaly. [2] They may cause aesthetic problems as they have a growth cycle, and can continue to grow throughout life. Vascular malformations of the brain include those involving capillaries, and those involving the veins and arteries.
The estimated prevalence of vascular anomalies is 4.5%. [2] Vascular anomalies can occur throughout the whole body, but in 60% of patients they are localized in the head and neck region. [3] Vascular anomalies can present in various ways: when situated deep below the skin, they appear blue, and are often called cavernous.
A cerebral AVM diagnosis is established by neuroimaging studies after a complete neurological and physical examination. [5] [13] Three main techniques are used to visualize the brain and search for an AVM: computed tomography (CT), magnetic resonance imaging (MRI), and cerebral angiography. [13]
An arteriovenous malformation (AVM) is an abnormal connection between arteries and veins, bypassing the capillary system. Usually congenital , this vascular anomaly is widely known because of its occurrence in the central nervous system (usually as a cerebral AVM ), but can appear anywhere in the body.
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In arteriovenous malformations, arteries are directly connected to veins, which increases the risk of venous rupture and hemorrhage. Cerebral arteriovenous malformations in the brain have a 2–4% chance of rupture each year. However, many arteriovenous malformations go unnoticed and are asymptomatic throughout a person's lifetime. [17]