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Uric acid displays lactam–lactim tautomerism. [4] Uric acid crystallizes in the lactam form, [5] with computational chemistry also indicating that tautomer to be the most stable. [6] Uric acid is a diprotic acid with pK a1 = 5.4 and pK a2 = 10.3. [7] At physiological pH, urate predominates in solution. [medical citation needed]
Cinnamic acid and its derivatives, such as ferulic acid - found in seeds of plants such as in brown rice, whole wheat and oats, as well as in coffee, apple, artichoke, peanut, orange and pineapple. Ellagic acid - found in high concentration in raspberry and strawberry , and in ester form in barrel-aged alcohol such as red wine and whisky.
Anchovy and its products like budu are high in protein and uric acid, [5] thus not recommended for people with gout. The uric acid content in anchovies, however, is lower than that in tuna. [citation needed] Budu made from anchovy sauce has shown potential as an anti-cancer agent. [6] As a food sourced from fish it also has potential as brain ...
Uric acid has the highest concentration of any blood antioxidant [58] and provides over half of the total antioxidant capacity of human serum. [64] Uric acid's antioxidant activities are also complex, given that it does not react with some oxidants, such as superoxide, but does act against peroxynitrite, [65] peroxides, and hypochlorous acid. [66]
The increase in antioxidant capacity of blood seen after the consumption of anthocyanin-rich foods may not be caused directly by the anthocyanins in the food, but instead by increased uric acid levels derived from metabolizing flavonoids (anthocyanin parent compounds) in the food. [52]
The main source of polyphenols is dietary, since they are found in a wide array of phytochemical-bearing foods.For example, honey; most legumes; fruits such as apples, blackberries, blueberries, cantaloupe, pomegranate, cherries, cranberries, grapes, pears, plums, raspberries, aronia berries, and strawberries (berries in general have high polyphenol content [5]) and vegetables such as broccoli ...