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Transferrin and beta-lipoprotein comprises the beta-1. Increased beta-1 protein due to the increased level of free transferrin is typical of iron deficiency anemia, pregnancy, and oestrogen therapy. Increased beta-1 protein due to LDL elevation occurs in hypercholesterolemia. Decreased beta-1 protein occurs in acute or chronic inflammation.
Schematic representation of a protein electrophoresis gel. Beta globulins are a group of globular proteins in plasma that are more mobile in alkaline or electrically charged solutions than gamma globulins, but less mobile than alpha globulins. [1] [2] [3] Examples of beta globulins include: beta-2 microglobulin; plasminogen; angiostatins; properdin
Alpha globulins; Beta globulins; Gamma globulins (one group of gamma globulins is the immunoglobulins, which are also known as "antibodies") Globulins can be distinguished from one another using serum protein electrophoresis. Globulins exert oncotic pressure. Their deficiency results in loss of carrier functions of globulins, oedema due to ...
Hyperproteinemia is the state of having overly high levels of protein in the blood. This can occur due to monoclonal gammopathies such as multiple myeloma and after intravenous immunoglobulin has been given. [1] It can result in a falsely low appearing sodium level (hyponatremia). [1]
Contrary to popular belief, haemoglobin is not a blood protein, as it is carried within red blood cells, rather than in the blood serum. Serum albumin accounts for 55% of blood proteins, [ 1 ] is a major contributor to maintaining the oncotic pressure of plasma and assists, as a carrier, in the transport of lipids and steroid hormones .
567 12010 Ensembl ENSG00000166710 ENSG00000273686 ENSMUSG00000060802 UniProt P61769 P01887 RefSeq (mRNA) NM_004048 NM_009735 RefSeq (protein) NP_004039 NP_033865 Location (UCSC) Chr 15: 44.71 – 44.72 Mb Chr 2: 121.98 – 121.98 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse β 2 microglobulin (B2M) is a component of MHC class I molecules. MHC class I molecules have α 1, α 2, and ...
Hypergammaglobulinemia is a condition that is characterized by the increased levels of a certain immunoglobulin in the blood serum. [1] The name of the disorder refers to an excess of proteins after serum protein electrophoresis (found in the gammaglobulin region). [citation needed]
Serum total protein, also known as total protein, is a clinical chemistry parameter representing the concentration of protein in serum. [1] Serum contains many proteins including serum albumin, a variety of globulins, and many others. While it is possible to analyze these proteins individually, total protein is a relatively quick and ...