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Methylephedrine, sold under the brand name Metheph among others, is a sympathomimetic medication described as an antiasthmatic agent and used to treat coughing and nasal congestion. [ 3 ] [ 4 ] [ 1 ] It is reported to be used in various over-the-counter cough and cold preparations throughout the world, including Japan .
Levmetamfetamine is used to treat nasal congestion related to the common cold and allergic rhinitis. It is available in the form of an inhaler containing 50 mg total per inhaler and delivering between 0.04 and 0.15 mg of the drug per inhalation. [2]
Their effectiveness by themselves in the common cold appears to have a small benefit in adults. [1] Topical decongestants should only be used by patients for a maximum of 5–7 days in a row, because rebound congestion may occur in the form of rhinitis medicamentosa. When used in adults for a short period of time side effects appear to be few. [1]
As a cough suppressant, the polistirex version lasts up to 12 hours. This duration also holds true when used recreationally. In 1981, a paper by Gosselin estimated that the lethal dose is between 50 and 500 mg/kg. Doses as high as 15–20 mg/kg are taken by some recreational users.
Propylhexedrine works mainly as an adrenergic agonist, when used at therapeutic doses in an inhaler dosage form. [21] This restricts the blood vessels in the nose and reduces swelling; thereby, it relieves nasal congestion. [22] At higher doses, propylhexedrine affects the central nervous system as a norepinephrine–dopamine releasing agent ...
The range contains 200 mg of guaifenesin which helps to relieve chesty cough, in addition to 1000 mg of paracetamol and 12.2 mg of phenylephrine hydrochloride (12.18 mg of phenylephrine hydrochloride in Lemsip Max All In One Liquid) which aims to relieve headache, sore throat, fever, body aches and pains, and a blocked nose.
Clenbuterol is approved for use in some countries as a bronchodilator for asthma. [medical citation needed]Clenbuterol is a β 2 agonist with some structural and pharmacological similarities to epinephrine and salbutamol, but its effects are more potent and longer-lasting as a stimulant and thermogenic drug.
Coricidin, Coricidin 'D' (decongestant), or Coricidin HBP (for high blood pressure), is the name of an over-the-counter cough and cold drug containing dextromethorphan (a cough suppressant) and chlorpheniramine maleate (an antihistamine). [1] Introduced by Schering-Plough in 1949 as one of the first antihistamines, it is now owned by Bayer.