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Arthritis of the knee is typically a particularly debilitating form of arthritis. [1] The knee may become affected by almost any form of arthritis. [2] The word arthritis refers to inflammation of the joints. [3][4] Types of arthritis include those related to wear and tear of cartilage, such as osteoarthritis, to those associated with ...
Articular cartilage damage is often the cause of severe pain, knee swelling, substantial reduction in mobility and severe restrictions to one's activities. Over the last decades, however, research has focused on regenerating damaged joints. These regenerative procedures are believed to delay osteoarthritis of injuries on the articular cartilage ...
Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone. [5][6] It is believed to be the fourth leading cause of disability in the world, affecting 1 in 7 adults in the United States alone. [7] The most common symptoms are joint pain and stiffness. [1]
Osteoarthritis is challenging to manage and impacts many people in the United States and worldwide. In the U.S., 21.2% of adults have been diagnosed with some type of arthritis. Worldwide, over ...
Gene therapy for osteoarthritis. Gene therapy for osteoarthritis is the application of gene therapy to treat osteoarthritis (OA). Unlike pharmacological treatments which are administered locally or systemically as a series of interventions, gene therapy aims to establish sustained therapeutic effect after a single, local injection. [1]
Knee pain is pain in or around the knee. The knee joint consists of an articulation between four bones: the femur, tibia, fibula and patella. There are four compartments to the knee. These are the medial and lateral tibiofemoral compartments, the patellofemoral compartment and the superior tibiofibular joint.
Osteoarthritis is a common condition of cartilage failure that can lead to limited range of motion, bone damage and invariably, pain. Due to a combination of acute stress and chronic fatigue, osteoarthritis directly manifests itself in a wearing away of the articular surface and, in extreme cases, bone can be exposed in the joint.
Relatively common [2] Patellofemoral pain syndrome (PFPS; not to be confused with jumper's knee) is knee pain as a result of problems between the kneecap and the femur. [4] The pain is generally in the front of the knee and comes on gradually. [2][4] Pain may worsen with sitting down with a bent knee for long periods of time, excessive use, or ...