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  2. Sister group - Wikipedia

    en.wikipedia.org/wiki/Sister_group

    The term sister group is used in phylogenetic analysis, however, only groups identified in the analysis are labeled as "sister groups".. An example is birds, whose commonly cited living sister group is the crocodiles, but that is true only when discussing extant organisms; [3] [4] when other, extinct groups are considered, the relationship between birds and crocodiles appears distant.

  3. Clade - Wikipedia

    en.wikipedia.org/wiki/Clade

    The crown age of a clade refers to the age of the most recent common ancestor of all of the species in the clade. The stem age of a clade refers to the time that the ancestral lineage of the clade diverged from its sister clade. A clade's stem age is either the same as or older than its crown age. [15] Ages of clades cannot be directly observed.

  4. Gene targeting - Wikipedia

    en.wikipedia.org/wiki/Gene_targeting

    Genetic modification usually describes the insertion of a transgene (foreign DNA, i.e. a gene from another species) into a random location within the genome. [ 13 ] [ 14 ] Gene-targeting is a specific biotechnological tool that can lead to small changes to the genome at a specific site [ 2 ] - in which case the edits caused by gene-targeting ...

  5. Genome editing - Wikipedia

    en.wikipedia.org/wiki/Genome_editing

    Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism. Unlike early genetic engineering techniques that randomly insert genetic material into a host genome, genome editing targets the insertions to site-specific locations.

  6. Human germline engineering - Wikipedia

    en.wikipedia.org/wiki/Human_germline_engineering

    Cas9 acts as a pair of ‘molecular scissors’ that can cut the DNA at a specific location in the genome so that genes can be added or removed. The guide RNA has complementary bases to those at the target location, so it binds only there. Once bound Cas9 makes a cut across both DNA strands allowing base pairs to inserted/removed.

  7. Modifications (genetics) - Wikipedia

    en.wikipedia.org/wiki/Modifications_(genetics)

    Genetic engineering is a type of intentional genetic modification, which uses biotechnology to alter an organism's genome. [ citation needed ] According to World Health Organization (WHO), genetically modified organisms are defined as "Organisms (i.e. plants, animals or microorganisms) in which the genetic material (DNA) has been altered in a ...

  8. Cladistics - Wikipedia

    en.wikipedia.org/wiki/Cladistics

    A clade is characterized by one or more apomorphies: derived character states present in the first member of the taxon, inherited by its descendants (unless secondarily lost), and not inherited by any other taxa. Paraphyly: A paraphyletic assemblage is one that is constructed by taking a clade and removing one or more smaller clades. [32]

  9. Gene editing - Wikipedia

    en.wikipedia.org/wiki/Gene_editing

    Gene editing may refer to: . Genetic engineering of any organism by genome editing. Gene editing is the emerging molecular biology technique which makes very specific targeted changes by insertion, deletion or substitution of genetic material in an organism's DNA to obtain desired results.

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