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  2. Glomerulus (kidney) - Wikipedia

    en.wikipedia.org/wiki/Glomerulus_(kidney)

    Glomerular mesangial cells structurally support the tufts. Blood enters the capillaries of the glomerulus by a single arteriole called an afferent arteriole and leaves by an efferent arteriole. [3] The capillaries consist of a tube lined by endothelial cells with a central lumen. The gaps between these endothelial cells are called fenestrae.

  3. Mesangial proliferative glomerulonephritis - Wikipedia

    en.wikipedia.org/wiki/Mesangial_proliferative_gl...

    Nephrology. Mesangial proliferative glomerulonephritis (MesPGN) is a morphological pattern characterized by a numerical increase in mesangial cells and expansion of the extracellular matrix within the mesangium of the glomerulus. [1] The increase in the number of mesangial cells can be diffuse or local and immunoglobulin and/or complement ...

  4. Mesangial cell - Wikipedia

    en.wikipedia.org/wiki/Mesangial_cell

    Mesangial cells are specialised cells in the kidney that make up the mesangium of the glomerulus. Together with the mesangial matrix, they form the vascular pole of the renal corpuscle. [1] The mesangial cell population accounts for approximately 30-40% of the total cells in the glomerulus. [2] Mesangial cells can be categorized as either ...

  5. Diabetic nephropathy - Wikipedia

    en.wikipedia.org/wiki/Diabetic_nephropathy

    Diabetic nephropathy, also known as diabetic kidney disease, [5] is the chronic loss of kidney function occurring in those with diabetes mellitus. Diabetic nephropathy is the leading causes of chronic kidney disease (CKD) and end-stage renal disease (ESRD) globally. The triad of protein leaking into the urine (proteinuria or albuminuria ...

  6. Glomerulonephritis - Wikipedia

    en.wikipedia.org/wiki/Glomerulonephritis

    Glomerulonephritis (GN) is a term used to refer to several kidney diseases (usually affecting both kidneys). Many of the diseases are characterised by inflammation either of the glomeruli or of the small blood vessels in the kidneys, hence the name, [1] but not all diseases necessarily have an inflammatory component. [citation needed]

  7. Membranoproliferative glomerulonephritis - Wikipedia

    en.wikipedia.org/wiki/Membranoproliferative_gl...

    Membranoproliferative glomerulonephritis (MPGN) is a type of glomerulonephritis caused by deposits in the kidney glomerular mesangium and basement membrane (GBM) thickening, [2] activating the complement system and damaging the glomeruli. MPGN accounts for approximately 4% of primary renal causes of nephrotic syndrome in children and 7% in adults.

  8. Intraglomerular mesangial cell - Wikipedia

    en.wikipedia.org/wiki/Intraglomerular_mesangial_cell

    Intraglomerular mesangial cells synthesize and secrete the extracellular matrix. It contains fibronectin, type IV collagen, perlecan, and laminin. Intraglomerular mesangial cells phagocytize glomerular basal lamina components and immunoglobulins. They are an unusual example of phagocytic cells derived from smooth muscle and not monocytes.

  9. Glomerulonephrosis - Wikipedia

    en.wikipedia.org/wiki/Glomerulonephrosis

    Glomerulonephrosis is a non-inflammatory disease of the kidney (nephrosis) presenting primarily in the glomerulus (a glomerulopathy) as nephrotic syndrome. The nephron is the functional unit of the kidney and it contains the glomerulus, which acts as a filter for blood to retain proteins and blood lipids.

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