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FL is the most prevalent form of indolent lymphoma, accounting for 70% of indolent cases and 20–30% of all non-Hodgkin lymphoma cases, with a yearly incidence of 1.6 to 3.1 per 100,000. [13] [15] It is most frequently diagnosed among people in their 50s and 60s, and is more common among white populations than black or Asian populations. [14]
The disorder resembled certain aggressive GI tract lymphomas and was variably termed indolent lymphoma or indolent T cell lymphoproliferative disorder of the gastrointestinal tract. [4] However, the disease differed from the aggressive lymphomas which it mimicked in having a prolonged and usually non-progressive course.
Of the many forms of lymphoma, some are categorized as indolent (e.g. small lymphocytic lymphoma), compatible with a long life even without treatment, whereas other forms are aggressive (e.g. Burkitt's lymphoma), causing rapid deterioration and death. However, most of the aggressive lymphomas respond well to treatment and are curable.
The Mayo Clinic Cancer Center is one of the oldest NCI-designated cancer centers in the United States, having first been designated in 1973. [3] The main location of the Mayo Clinic is in Rochester, MN. Campuses in Arizona and Florida opened later and became part of the Mayo Clinic Cancer Center in 2003. [4] [5] Mayo receives more than $100 ...
Mayo Clinic Health System - Mankato, formerly known as Immanuel-St. Joseph's Hospital, is a general medical and surgical hospital in Mankato, Minnesota. It has been a part of Mayo Clinic since 1996. Immanuel-St. Joseph's was formed in 1969 from a merger between two Mankato hospitals, Immanuel Hospital (established 1906) and St. Joseph's ...
Indolent condition is a condition that continues for a prolonged period. [1] Examples include: Indolent chronic lymphocytic leukemia or indolent CLL, which is a slow-progressing blood and bone marrow cancer, [2] Indolent lymphoma or low-grade lymphoma, a type of slow-growing non-Hodgkin lymphoma or slow-growing NHL. [3]
B-cell lymphoma-2 inhibitor, venetoclax, plus a CD20 antibody obinutuzumab, OR; BTKi (i.e. ibrutinib) plus BCL-2 inhibitor (i.e. venetoclax) [15] [16] [17] CLL is the most common type of leukemia in the Western world. It most commonly affects individuals over the age of 65, due to the accumulation of genetic mutations that occur over time.
The use of rituximab has been established for the treatment of B-cell–derived hematologic malignancies, including follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL). [ 7 ] In addition to cure-directed treatment, people can benefit from self-care to manage symptoms.