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HIV-1 is most similar to the SIV found in common chimpanzees (SIVcpz) in southeastern Cameroon, giving rise to the notion that HIV-1 emerged from chimpanzees in this area. [4] SIVcpz itself emerged in chimpanzees as the result of a recombination of two separate lineages of SIV known to infect red-capped mangabey, and Cercopithecus species. [3] [5]
Several of the theories of HIV origin accept the established knowledge of the HIV/SIV phylogenetic relationships, and also accept that bushmeat practice was the most likely cause of the initial transfer to humans. All of them propose that the simultaneous epidemic emergences of four HIV groups in the late 19th-early 20th century, and the lack ...
Simian immunodeficiency virus (SIV) is a species of retrovirus that cause persistent infections in at least 45 species of non-human primates. [1] [2] Based on analysis of strains found in four species of monkeys from Bioko Island, which was isolated from the mainland by rising sea levels about 11,000 years ago, it has been concluded that SIV has been present in monkeys and apes for at least ...
The Oral polio vaccine AIDS hypothesis (OPV AIDS) is a now-discredited hypothesis which argued the AIDS pandemic originated from live polio vaccines prepared in chimpanzee tissue cultures, accidentally contaminated with simian immunodeficiency virus and then administered to up to one million Africans between 1957 and 1960 in experimental mass vaccination campaigns.
HIV-1 is thought to have jumped the species barrier on at least three separate occasions, giving rise to the three groups of the virus, M, N, and O. [164] Left to right: the African green monkey source of SIV, the sooty mangabey source of HIV-2, and the chimpanzee source of HIV-1
HIV-1 appears to have originated in southern Cameroon through the evolution of SIV(cpz), a simian immunodeficiency virus (SIV) that infects wild chimpanzees (HIV-1 descends from the SIVcpz endemic in the chimpanzee subspecies Pan troglodytes troglodytes).
English: Phylogenetic Tree of the SIV and HIV viruses. Viruses Depicted in HIV-SIV Phylogenetic Tree; Human HIV-1 M (Main) group, including reference strains from subtypes A-J. Group M is responsible for the pandemic. HIV-1 O (Outlier) group, most commonly found in West Africa HIV-1 N (Not-M, Not-O) group, found in a very small number of ...
This proved that the origin of a subspecies' chimpanzee host was what was responsible for two different phylogenetic lineages of SIVcpz strains. Hahn's careful phylogenetic analysis also supported that the source of HIV-1 was the chimpanzees that were members of P.t. troglodytes. [13]
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