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Shinya Yamanaka speaking at a lecture on 2010 January 14. Yamanaka and Ryōji Noyori participating in the ceremony of the 50th All Japan Rugby Football Championship. Shinya Yamanaka (山中 伸弥, Yamanaka Shin'ya, born September 4, 1962) is a Japanese stem cell researcher and a Nobel Prize laureate. [2][3][4] He is a professor and the ...
Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from a somatic cell. The iPSC technology was pioneered by Shinya Yamanaka and Kazutoshi Takahashi in Kyoto, Japan, who together showed in 2006 that the introduction of four specific genes (named Myc, Oct3/4, Sox2 ...
Institutions. Morgridge Institute for Research. University of Wisconsin, Madison. University of California, Santa Barbara. James Alexander Thomson is an American developmental biologist best known for deriving the first human embryonic stem cell line in 1998 [1] and for deriving human induced pluripotent stem cells (iPS) in 2007. [2]
Sir John Bertrand Gurdon FRS (born 2 October 1933) is a British developmental biologist, best known for his pioneering research in nuclear transplantation [2][3][4] and cloning. [1][5][6][7] Awarded the Lasker Award in 2009, in 2012, he and Shinya Yamanaka were jointly awarded the Nobel Prize for Physiology or Medicine for the discovery that ...
In 2006, Shinya Yamanaka's team in Kyoto, Japan converted fibroblasts into pluripotent stem cells by modifying the expression of only four genes. The feat represents the origin of induced pluripotent stem cells, known as iPS cells.
Mouse Embryonic Fibroblasts (MEFs) are a type of fibroblast prepared from mouse embryo. MEFs show a spindle shape when cultured in vitro, a typical feature of fibroblasts. The MEF is a limited cell line. After several transmissions, MEFs will senesce and finally die off. Nevertheless, researchers can use several strategies, like virus infection ...
The first Nobel Prize in Physiology or Medicine was awarded in 1901 to Emil Adolf von Behring, of Germany. Each recipient receives a medal, a diploma and a monetary award that has varied throughout the years. [ 4 ] In 1901, von Behring received 150,782 SEK, which was equal to 7,731,004 SEK in December 2008.
A single cardiomyocyte beating, five days after purification from cell culture.ogv. English: Single beating cell at day 5 after VCAM1 sorting. (MP4) Date. 18 August 2011. Source. Movie S2 from Uosaki H, Fukushima H, Takeuchi A, Matsuoka S, Nakatsuji N, Yamanaka S, Yamashita J. "Efficient and Scalable Purification of Cardiomyocytes from Human ...