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Autogenous vaccines, also called autologous vaccines, autovaccines, “self” or custom vaccines, are vaccines that are prepared by isolation and destruction of microorganisms in infected individuals and used to provide immunity to the same individual.
Autogenous biologics are custom vaccines that consist of herd specific (homologous) antigens. They are licensed products, produced in a licensed facility, according to an approved Outline of Production. Autogenous biologics are approved for use by or under the direction of a veterinarian or approved non-veterinarian specialist.
Thus, autogenous vaccines might be able to fill this gap and contribute to the reduction of antimicrobial usage. To the authors’ knowledge, there are no published studies investigating whether autogenous vaccines against S hyicus can reduce antimicrobial usage during severe EE outbreaks.
An autogenous vaccine is custom made for a specific producer or group of animals. This vaccine is a killed vaccine and needs to be made by a veterinarian. The efficacy (how well it works) does not need to be proven with an autogenous vaccine.
Autogenous vaccines against non-notifiable diseases are a complementary tool in veterinary medicine when a licensed vaccine 1 is not available for treatment and control of infectious diseases in animals. They have gained increased importance over the years in particular due to the efforts to reduce the use of antibiotics.
Abstract. An international meeting, held in Munich, Germany, on 14-16 September 2021, explored the expectations and views of different stakeholders regarding the implementation of the new veterinary medicines Regulation (Regulation (EU) 2019/6) in respect to inactivated autogenous vaccines (AVs) in non-notifiable diseases.
Autogenous vaccines are another vaccination strategy commonly developed as a targeted approach against highly virulent bacterial or viral strains affecting an individual herd (Hoelzer et al., 2018). From: Veterinary Microbiology, 2021