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  2. Depolarization - Wikipedia

    en.wikipedia.org/wiki/Depolarization

    In biology, depolarization or hypopolarization [1][2] is a change within a cell, during which the cell undergoes a shift in electric charge distribution, resulting in less negative charge inside the cell compared to the outside. Depolarization is essential to the function of many cells, communication between cells, and the overall physiology of ...

  3. Threshold potential - Wikipedia

    en.wikipedia.org/wiki/Threshold_potential

    In electrophysiology, the threshold potential is the critical level to which a membrane potential must be depolarized to initiate an action potential. In neuroscience, threshold potentials are necessary to regulate and propagate signaling in both the central nervous system (CNS) and the peripheral nervous system (PNS).

  4. Action potential - Wikipedia

    en.wikipedia.org/wiki/Action_potential

    As an action potential (nerve impulse) travels down an axon there is a change in electric polarity across the membrane of the axon. In response to a signal from another neuron, sodium- (Na +) and potassium- (K +)–gated ion channels open and close as the membrane reaches its threshold potential. Na + channels open at the beginning of the ...

  5. Cardiac conduction system - Wikipedia

    en.wikipedia.org/wiki/Cardiac_conduction_system

    The cardiac conduction system (CCS, also called the electrical conduction system of the heart) [1] transmits the signals generated by the sinoatrial node – the heart 's pacemaker, to cause the heart muscle to contract, and pump blood through the body's circulatory system. The pacemaking signal travels through the right atrium to the ...

  6. Cardiac action potential - Wikipedia

    en.wikipedia.org/wiki/Cardiac_action_potential

    Rate dependence of the action potential is a fundamental property of cardiac cells and alterations can lead to severe cardiac diseases including cardiac arrhythmia and sometimes sudden death. [3] Action potential activity within the heart can be recorded to produce an electrocardiogram (ECG). This is a series of upward and downward spikes ...

  7. Electrocardiography - Wikipedia

    en.wikipedia.org/wiki/Electrocardiography

    Use of real time monitoring of the heart in an intensive care unit in a German hospital (2015), the monitoring screen above the patient displaying an electrocardiogram and various values of parameters of the heart like heart rate and blood pressure. Electrocardiography is the process of producing an electrocardiogram (ECG or EKG[a]), a ...

  8. Cortical spreading depression - Wikipedia

    en.wikipedia.org/wiki/Cortical_spreading_depression

    Cortical spreading depression (CSD) or spreading depolarization (SD) is a wave of electrophysiological hyperactivity followed by a wave of inhibition. [1] Spreading depolarization describes a phenomenon characterized by the appearance of depolarization waves of the neurons and neuroglia [ 2 ] that propagates across the cortex at a velocity of 1 ...

  9. Afterdepolarization - Wikipedia

    en.wikipedia.org/wiki/Afterdepolarization

    Afterdepolarizations are abnormal depolarizations of cardiac myocytes that interrupt phase 2, phase 3, or phase 4 of the cardiac action potential in the electrical conduction system of the heart. Afterdepolarizations may lead to cardiac arrhythmias. Afterdepolarization is commonly a consequence of myocardial infarction, cardiac hypertrophy, or ...