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  2. Hydroxocobalamin - Wikipedia

    en.wikipedia.org/wiki/Hydroxocobalamin

    Hydroxocobalamin is the natural form of vitamin B 12 and a member of the cobalamin family of compounds. [6] [7] It is found in both raw and cooked beef, together with other cobalamins. [8] Hydroxocobalamin, or another form of vitamin B 12, are required for the body to make DNA. [7] Hydroxocobalamin was first isolated in 1949. [9]

  3. Vitamin B12 deficiency - Wikipedia

    en.wikipedia.org/wiki/Vitamin_B12_deficiency

    Hydroxocobalamin injection is a clear red liquid solution. Treatment should take into account the cause and severity of the condition. [6] Treatment is done by vitamin B 12 supplementation, either by mouth or by injection. [3] Initially in high daily doses, followed by less frequent lower doses, as the condition improves. [3]

  4. Vitamin B12 - Wikipedia

    en.wikipedia.org/wiki/Vitamin_B12

    Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. [2] It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. [3]

  5. Loading dose - Wikipedia

    en.wikipedia.org/wiki/Loading_dose

    A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life. Such drugs need only a low maintenance dose in order to keep the amount of the drug in the body at the appropriate therapeutic level, but this also means that, without an initial higher dose, it would take a long ...

  6. Vitamin B12 total synthesis - Wikipedia

    en.wikipedia.org/wiki/Vitamin_B12_total_synthesis

    The structure of vitamin B 12 was the first low-molecular weight natural product determined by x-ray analysis rather than by chemical degradation. Thus, while the structure of this novel type of complex biomolecule was established, its chemistry remained essentially unknown; exploration of this chemistry became one of the tasks of the vitamin's chemical synthesis.

  7. B vitamins - Wikipedia

    en.wikipedia.org/wiki/B_vitamins

    B vitamins are a class of water-soluble vitamins that play important roles in cell metabolism and synthesis of red blood cells. [1][2] They are a chemically diverse class of compounds. [1] Dietary supplements containing all eight are referred to as a vitamin B complex. Individual B vitamins are referred to by B-number or by chemical name, such ...

  8. Calcium channel blocker toxicity - Wikipedia

    en.wikipedia.org/wiki/Calcium_channel_blocker...

    Calcium channel blocker toxicity. Calcium channel blocker toxicity is the taking of too much of the medications known as calcium channel blockers (CCBs), either by accident or on purpose. [3] This often causes a slow heart rate and low blood pressure. [1] This can progress to the heart stopping altogether. [2]

  9. Cyanocobalamin - Wikipedia

    en.wikipedia.org/wiki/Cyanocobalamin

    Cyanocobalamin is a form of vitamin B. 12 used to treat and prevent vitamin B. 12 deficiency except in the presence of cyanide toxicity. [7][8][2] The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer.