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Alendronic acid, sold under the brand name Fosamax among others, is a bisphosphonate medication used to treat osteoporosis and Paget's disease of bone. [4] It is taken by mouth. [ 4 ] Use is often recommended together with vitamin D , calcium supplementation , and lifestyle changes.
Bisphosphonates are used to treat osteoporosis, osteitis deformans (Paget's disease of the bone), bone metastasis (with or without hypercalcemia), multiple myeloma, and other conditions involving fragile, breakable bone. In osteoporosis and Paget's, the most popular first-line bisphosphonate drugs are alendronate and risedronate.
Dr. Sarah Fishman, MD, PhD, an endocrinologist in New York City, agrees that a bone density scan is the best way to know how healthy your bones are. “Unfortunately, osteoporosis and osteopenia ...
Bone tissue is a dynamic system with active metabolism. [24] Bone tissue remodelling or bone remodeling is a successive chain of old bone matrix removal and its replacement with a new one. [25] These processes make a child’s skeleton grow and extend, while childhood is characterized by bone tissue growth rather than its resorption.
Medical research also supports the use of medications of the bisphosphonate class, such as pamidronate, to increase bone density. [21] Bisphosphonates are especially effective in children; [22] however, it is unclear if they either increase quality of life or decrease the rate of fracture incidence. [7]
When on treatment with bisphosphonates rechecking bone mineral density is not needed. [174] There is tentative evidence of benefit in males with osteoporosis. [178] Fluoride supplementation does not appear to be effective in postmenopausal osteoporosis, as even though it increases bone density, it does not decrease the risk of fractures. [179 ...