Search results
Results From The WOW.Com Content Network
Pleomorphic adenoma (or benign mixed tumor) is a common benign salivary gland neoplasm characterised by neoplastic proliferation of epithelial (ductal) cells along with myoepithelial components, having a malignant potentiality.
In approximately 75% of cases ca ex PAs arise in a pleomorphic adenoma that is apparent when the tumour is excised. [2] In the other approximately 25% of cases the individual had a pleomorphic adenoma excised previously and the diagnosis is made based on (1) the presence of a carcinoma, and (2) the history of a pleomorphic adenoma at that location.
Benign tumour of the submandibular gland, also known as pleomorphic adenoma, presented as a painless neck mass in a 40-year-old man. At the left of the image is the white tumour with its characteristic cartilaginous cut surface. To the right is the normally lobated submandibular salivary gland. Warthin's tumor; Myoepithelioma; Basal cell ...
In a case of benign tumor, such as pleomorphic adenoma, a significant outcome is also the rate of tumor recurrence. Pleomorphic adenomas may recur after a very long time from primary surgery, on average over 7–10 years and up to 24 years. [10] [11] Survival rates due to malignancy depends on the patient and extent of disease. [4]
An adenoma is a benign tumor of epithelial tissue with glandular origin, glandular characteristics, or both. Adenomas can grow from many glandular organs , including the adrenal glands , pituitary gland , thyroid , prostate , and others.
The myoepithelial cells may be spindled, plasmacytoid, eithelioid or clear. Tubules or epithelium are absent, or present in a small amount (<5%) by definition. Tumours with myoepithelial cells and a large amount of tubules are classified as pleomorphic adenomas (which must also contain the characteristic chondromyxoid stroma, which is normally absent in myoepithelioma).
Relative incidence of parotid tumors, showing carcinoma ex pleomorphic adenoma at right. [ 8 ] Relative incidence of submandibular tumors, showing carcinoma ex pleomorphic adenoma at bottom-right.
Polymorphous low-grade adenocarcinoma (PLGA) is a rare, asymptomatic, slow-growing malignant salivary gland tumor. [1] It is most commonly found in the palate. [2]The name of the tumor derives from the fact that: