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  2. Polycyclic aromatic hydrocarbon - Wikipedia

    en.wikipedia.org/wiki/Polycyclic_aromatic...

    A Polycyclic aromatic hydrocarbon (PAH) is a class of organic compounds that is composed of multiple aromatic rings. Most are produced by the incomplete combustion of organic matter — by engine exhaust fumes, tobacco, incinerators, in roasted meats and cereals, [ 1 ] or when biomass burns at lower temperatures as in forest fires .

  3. Why Early Diagnosis of PAH is So Important - AOL

    www.aol.com/why-early-diagnosis-pah-important...

    Oct. 31—(StatePoint) Each year, 500 to 1,000 people in the United States are diagnosed with pulmonary arterial hypertension (PAH). Because this progressive, chronic disorder is rare, it is often ...

  4. Merck's therapy for rare lung condition shown to help reduce ...

    www.aol.com/news/mercks-therapy-rare-lung...

    Winrevair was approved to treat pulmonary arterial hypertension (PAH), a progressive disorder caused by a constriction of arteries in the lungs, leading to symptoms such as shortness of breath ...

  5. Pulmonary arterial hypertension - Wikipedia

    en.wikipedia.org/.../Pulmonary_arterial_hypertension

    PAH is definitively diagnosed with a right heart catheterization showing a mean pulmonary arterial pressure greater than 20 mmHg at rest, with a pulmonary vascular resistance being 3 Woods Units or greater (indicative of pulmonary hypertension in the pre-capillary vasculature; the arteries and arterioles), and a pulmonary artery wedge pressure ...

  6. FDA approves new drug that may help stop a rare, fatal ... - AOL

    www.aol.com/fda-approves-drug-may-help-213035907...

    Winrevair is a biologic drug designed to grab onto and trap proteins called activins that are overproduced in PAH. These proteins cause the walls of a person’s blood vessels to keep growing and ...

  7. Actelion - Wikipedia

    en.wikipedia.org/wiki/Actelion

    Tracleer was the first oral treatment approved for pulmonary arterial hypertension, a rare, chronic, life-threatening disorder that severely compromises the functions of the lungs and heart. It is a dual endothelin receptor antagonist , see also: Endothelin receptor antagonist .

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