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A myotome is the group of muscles that a single spinal nerve innervates. [1] Similarly a dermatome is an area of skin that a single nerve innervates with sensory fibers. Myotomes are separated by myosepta (singular: myoseptum). [2] In vertebrate embryonic development, a myotome is the part of a somite that develops into muscle.
During embryogenesis, the dermomyotome and/or myotome in the somites contain the myogenic progenitor cells that will evolve into the prospective skeletal muscle. [9] The determination of dermomyotome and myotome is regulated by a gene regulatory network that includes a member of the T-box family, tbx6, ripply1, and mesp-ba. [10]
The myotome is that part of a somite that forms the muscles of the animal. [2] Each myotome divides into an epaxial part (epimere), at the back, and a hypaxial part (hypomere) at the front. [2] The myoblasts from the hypaxial division form the muscles of the thoracic and anterior abdominal walls.
Myotome is the group of muscles that a single spinal nerve root innervates. Myotome may also refer to: Myotome (embryology) , part of a somite that forms the muscles of the animal
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In technical terms, this means that somitogenesis occurs due to the largely cell-autonomous oscillations of a network of genes and gene products, which causes cells to oscillate between a permissive and a non-permissive state in a consistently timed-fashion, like a clock.
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17928 Ensembl ENSG00000122180 ENSMUSG00000026459 UniProt P15173 P12979 RefSeq (mRNA) NM_002479 NM_031189 RefSeq (protein) NP_002470 NP_112466 Location (UCSC) Chr 1: 203.08 – 203.09 Mb Chr 1: 134.22 – 134.22 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Myogenin, is a transcriptional activator encoded by the MYOG gene. Myogenin is a muscle-specific basic-helix-loop-helix (bHLH ...