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However, these cells did not self-renew and were subsequently depleted as they generated new neurons, thus failing to satisfy the requirement for stem cells. [6] [7] One study observed that ependymal cells from the lining of the lateral ventricle might be a source for cells which can be transplanted into the cochlea to reverse hearing loss. [8]
This schematic illustrates the four different types of glial cells, all of which possess cytoplasmic processes: ependymal cells (light pink), astrocytes (green), microglia (red), and oligodendrocytes (light blue). Cell bodies of neurons are in yellow (Their axons are surrounded by myelin, produced by oligodendrocytes).
Tanycytes are highly specialized ependymal cells found in the third ventricle of the brain, and on the floor of the fourth ventricle. Each tanycyte has a long basal process that extends deep into the hypothalamus. It is possible that their function is to transfer chemical signals from the cerebrospinal fluid to the central nervous system.
Ependymal cells: Ependymal cells, also named ependymocytes, line the spinal cord and the ventricular system of the brain. These cells are involved in the creation and secretion of cerebrospinal fluid (CSF) and beat their cilia to help circulate the CSF and make up the blood-CSF barrier. They are also thought to act as neural stem cells. [15] CNS
Brain cells make up the functional tissue of the brain. The rest of the brain tissue is the structural stroma that includes connective tissue such as the meninges, blood vessels, and ducts. The two main types of cells in the brain are neurons, also known as nerve cells, and glial cells, also known as neuroglia. [1]
The central canal (also known as spinal foramen or ependymal canal) is the cerebrospinal fluid-filled space that runs through the spinal cord. [1] The central canal lies below and is connected to the ventricular system of the brain , from which it receives cerebrospinal fluid, and shares the same ependymal lining.
Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates.. CSF is produced by specialized ependymal cells in the choroid plexus of the ventricles of the brain, and absorbed in the arachnoid granulations.
Progenitor ependymal cells are monociliated but they differentiate into multiciliated ependymal cells. [6] [7] Unlike the ependyma, the choroid plexus epithelial layer has tight junctions [8] between the cells on the side facing the ventricle (apical surface). These tight junctions prevent the majority of substances from crossing the cell layer ...