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Intravenous sodium bicarbonate is contraindicated in patients who are losing chloride, such as by vomiting. [9]Because of its sodium content, intravenous sodium bicarbonate should be used with great care, if at all, in patients with congestive heart failure and severe chronic kidney disease, where low sodium intake is strongly indicated to prevent sodium retention. [9]
Alkalinizing agents are drugs used to manage disorders associated with low pH. For example, they may be used to treat acidosis due to kidney failure. Used for oral or parenteral therapy, sodium bicarbonate is the commonly preferred alkalinizing agent. [1] Others include potassium citrate, calcium carbonate, sodium lactate and calcium acetate. [2]
Sodium bicarbonate reacts spontaneously with acids, releasing CO 2 gas as a reaction product. It is commonly used to neutralize unwanted acid solutions or acid spills in chemical laboratories. [32] It is not appropriate to use sodium bicarbonate to neutralize base [33] even though it is amphoteric, reacting with both acids and bases. [34]
The carbon dioxide is generated by a reaction of a compound containing bicarbonate, such as sodium bicarbonate or magnesium bicarbonate, with an acid such as citric acid or tartaric acid. Both compounds are present in the tablet in powder form and start reacting as soon as they dissolve in water. [1] [2] [3] [4]
Examples of important inorganic sodium salts are sodium fluoride, sodium chloride, sodium bromide, sodium iodide, sodium sulfate, sodium bicarbonate and sodium carbonate. Sodium amide (NaNH 2) is the sodium salt of ammonia (NH 3).
Eno was first marketed by James Crossley Eno (1827–1915). [4] Legend has it that his idea for the product arose while he was working at the pharmacy of an infirmary in Newcastle, Britain, with Dennis Embleton; Embleton often prescribed an effervescent drink made by mixing sodium bicarbonate and citric acid in water, and Eno adopted this beverage. [5]
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