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Gastric erosion occurs when the mucous membrane lining the stomach becomes inflamed. Specifically, the term "erosion" in this context means damage that is limited to the mucosa, which consists of three distinct layers: the epithelium (in the case of a healthy stomach, this is non-ciliated simple columnar epithelium), the basement membrane, and the lamina propria.
The appendix has a mucosa resembling the colon but is heavily infiltrated with lymphocytes. Transition between the different types of epithelium occurs at the junction between the oesophagus and stomach; between the stomach and duodenum, between the ileum and caecum, and at the pectinate line of the anus. [1]
Gastric ulcers may develop; it is unclear if they are the causes or the consequences. Intestinal metaplasia typically begins in response to chronic mucosal injury in the antrum and may extend to the body. Gastric mucosa cells change to resemble intestinal mucosa and may even assume absorptive characteristics.
Diagram of the alkaline mucous layer in the stomach with mucosal defense mechanisms. The gastric mucosa is the mucous membrane layer of the stomach, which contains the gastric pits, to which the gastric glands empty. In humans, it is about one mm thick, and its surface is smooth, soft, and velvety.
A Cameron lesion is a linear erosion or ulceration of the mucosal folds lining the stomach where it is constricted by the thoracic diaphragm in persons with large hiatal hernias. [1] The lesions may cause chronic blood loss resulting in iron deficiency anemia ; less often they cause acute bleeding.
Ulcers cause breaks in the mucosa and cause erosion of the sub-mucosa. Zollinger-Ellison syndrome Gastrin levels increase due to tumors, which cause an increase in the gastric fold size. [7] Ménétrier's disease The mucosa pits are in excess causing thickening of the folds. [7] Carcinoma Helicobacter pylori infection Causes inflammation of the ...
In the stomach there is a slight balance between acid and the wall lining which is protected by mucus. When this mucus lining is disrupted for whatever reason, signs and symptoms of acidity result. This may result in upper abdominal pain, indigestion, loss of appetite, nausea, vomiting and heartburn. When the condition is allowed to progress ...
Peptic ulcer disease is when the inner part of the stomach's gastric mucosa (lining of the stomach), the first part of the small intestine, or sometimes the lower esophagus, gets damaged. An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer. [1]