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The majority of people struck with MDR-TB live in "resource-poor settings" and are denied treatment because international organizations have refused to make technologies available to countries who cannot afford to pay for treatment, the reason being that second line drugs are too expensive therefore treatment methods for MDR-TB are not ...
Treatment options can often be ranked or prioritized into lines of therapy: first-line therapy, second-line therapy, third-line therapy, and so on. First-line therapy (sometimes referred to as induction therapy , primary therapy , or front-line therapy ) [ 6 ] is the first therapy that will be tried.
Capreomycin is an antibiotic which is given in combination with other antibiotics for the treatment of tuberculosis. [1] Specifically it is a second line treatment used for active drug resistant tuberculosis. [1] It is given by injection into a vein or muscle. [1]
Bismuth-based quadruple therapy is recommended as first line therapy for patients in areas with high clarithromycin resistance (> 20%), in patients who have previously been treated with a macrolide antibiotic, or as second-line therapy for patients whose infection persists after an initial course of triple therapy.
Linezolid is also an acceptable second-line treatment for community-acquired pneumococcal pneumonia when penicillin resistance is present. [31] U.S. guidelines recommend either linezolid or vancomycin as the first-line treatment for hospital-acquired (nosocomial) MRSA pneumonia. [33]
In places where infections are not common, it is a second line treatment after paromomycin when a person has no symptoms. [2] For people who are symptomatic, it is used after treatment with metronidazole or tinidazole. [2] It is taken by mouth. [1] Diloxanide generally has mild side effects. [3]
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