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In this diagram of a duplicated chromosome, (2) identifies the centromere—the region that joins the two sister chromatids, or each half of the chromosome. In prophase of mitosis, specialized regions on centromeres called kinetochores attach chromosomes to spindle fibers. The centromere links a pair of sister chromatids together during cell ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 22 February 2025. DNA molecule containing genetic material of a cell This article is about the DNA molecule. For the genetic algorithm, see Chromosome (genetic algorithm). Chromosome (10 7 - 10 10 bp) DNA Gene (10 3 - 10 6 bp) Function A chromosome and its packaged long strand of DNA unraveled. The DNA's ...
The presence of a vestigial centromere. Normally a chromosome has just one centromere, but in chromosome 2 there are remnants of a second centromere in the q21.3–q22.1 region. [12] The presence of vestigial telomeres. These are normally found only at the ends of a chromosome, but in chromosome 2 there are additional telomere sequences in the ...
Role of the centrosome in cell cycle progression. Centrosomes are associated with the nuclear membrane during the prophase stage of the cell cycle. During mitosis, the nuclear membrane breaks down, and the centrosome-nucleated microtubules can interact with the chromosomes to build the mitotic spindle.
The sister chromatids will be distributed to each daughter cell at the end of the cell division. Whereas if the chromosome is isobrachial (centromere at centre and arms of equal length), the p and q system is meaningless. At either end of a chromosome is a telomere, a cap of DNA that protects the rest of the chromosome from damage.
The centromere of chromosome 6 illustrates an interesting example of centromere evolution. It was known [ further explanation needed ] that in a Catarrhini ancestor the chromosome 6 centromere was situated near position 26 Mb of the modern human chromosome.
In prophase of mitosis, specialized regions on centromeres called kinetochores attach chromosomes to spindle fibers. The monocentric chromosome is a chromosome that has only one centromere in a chromosome and forms a narrow constriction. Monocentric centromeres are the most common structure on highly repetitive DNA in plants and animals. [1]
pseudo dicentric – only one centromere in a dicentric chromosome is active q: Long arm of a chromosome r: Ring chromosome t: Translocation: ter: Terminal end of arm (e.g. 2qter refers to the end of the long arm of chromosome 2) tri: Trisomy: trp: Triplication of a portion of a chromosome