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In hematology, thrombocythemia is a condition of high platelet (thrombocyte) count in the blood. Normal count is in the range of 150 × 10 9 to 450 × 10 9 platelets per liter of blood, [ 1 ] but investigation is typically only considered if the upper limit exceeds 750 × 10 9 /L.
A reference range is usually defined as the set of values 95 percent of the normal population ... Platelet count (Plt) ... though smaller in other children. Female ...
A complete blood count (CBC), also known as a full blood count (FBC), is a set of medical laboratory tests that provide information about the cells in a person's blood.The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin, and the hematocrit (the volume percentage of red blood cells).
Low levels of platelets in turn may lead to prolonged or excessive bleeding. It is the most common coagulation disorder among intensive care patients and is seen in a fifth of medical patients and a third of surgical patients. [3] A normal human platelet count ranges from 150,000 to 450,000 platelets/microliter (μL) of blood. [4]
Gestational (incidental) thrombocytopenia is a condition that commonly affects pregnant women.Thrombocytopenia is defined as the drop in platelet count from the normal range of 150,000–400,000/μL to a count lower than 150,000/μL. [1]
[67] [68] Platelets were described in the early 19th century, and in the 1880s several investigators linked the purpura with abnormalities in the platelet count. [ 67 ] [ 69 ] The first report of a successful therapy for ITP was in 1916, when a young Polish medical student, Paul Kaznelson , described a female patient's response to a splenectomy ...
Platelet concentration in the blood (i.e. platelet count), can be measured manually using a hemocytometer, or by placing blood in an automated platelet analyzer using particle counting, such as a Coulter counter or optical methods. [47] Most common blood testing methods include platelet count in their measurements, usually reported as PLT. [48]
In children, these white blood cell-platelet aggregates are increased in children compared to adult levels, however this takes place without a corresponding increase in platelet activation. [10] Increased white blood cell-platelet aggregates in adults can indicate atherosclerosis, but this is not the case in children.